Publication: Amplification-free profiling of microRNA-122 biomarker in DILI patient serums, using the luminex MAGPIX system.
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2020-06-29
Authors
Marín-Romero, Antonio
Tabraue-Chávez, Mavys
Dear, James W
Sánchez-Martín, Rosario M
Ilyine, Hugh
Guardia-Monteagudo, Juan J
Fara, Mario A
López-Delgado, Francisco J
Díaz-Mochón, Juan J
Pernagallo, Salvatore
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Abstract
Dynamic chemical labelling is a single-base specific method to enable detection and quantification of micro-Ribonucleic Acids in biological fluids without extraction and pre-amplification. In this study, dynamic chemical labelling was combined with the Luminex MAGPIX system to profile levels of microRNA-122 biomarker in serum from patients with Drug-Induced Liver Injury.
Description
MeSH Terms
Biomarkers
Chemical and Drug Induced Liver Injury
Humans
MicroRNAs
Chemical and Drug Induced Liver Injury
Humans
MicroRNAs
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Keywords
Drug-induced liver injury (DILI), Dynamic chemical labelling (DCL), Liquid biopsy, Luminex MAGPIX, miRNA-122