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Iron deficiency is associated with Hypothyroxinemia and Hypotriiodothyroninemia in the Spanish general adult population: Di@bet.es study.

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dc.contributor.authorMaldonado-Araque, Cristina
dc.contributor.authorValdés, Sergio
dc.contributor.authorLago-Sampedro, Ana
dc.contributor.authorLillo-Muñoz, Juan Antonio
dc.contributor.authorGarcia-Fuentes, Eduardo
dc.contributor.authorPerez-Valero, Vidal
dc.contributor.authorGutierrez-Repiso, Carolina
dc.contributor.authorGoday, Albert
dc.contributor.authorUrrutia, Ines
dc.contributor.authorPeláez, Laura
dc.contributor.authorCalle-Pascual, Alfonso
dc.contributor.authorCastaño, Luis
dc.contributor.authorCastell, Contxa
dc.contributor.authorDelgado, Elias
dc.contributor.authorMenendez, Edelmiro
dc.contributor.authorFranch-Nadal, Josep
dc.contributor.authorGaztambide, Sonia
dc.contributor.authorGirbés, Joan
dc.contributor.authorOrtega, Emilio
dc.contributor.authorVendrell, Joan
dc.contributor.authorChacón, Matilde R
dc.contributor.authorChaves, Felipe J
dc.contributor.authorSoriguer, Federico
dc.contributor.authorRojo-Martínez, Gemma
dc.date.accessioned2023-01-25T10:07:37Z
dc.date.available2023-01-25T10:07:37Z
dc.date.issued2018-04-26
dc.description.abstractPrevious studies have suggested that iron deficiency (ID) may impair thyroid hormone metabolism, however replication in wide samples of the general adult population has not been performed. We studied 3846 individuals free of thyroid disease, participants in a national, cross sectional, population based study representative of the Spanish adult population. Thyroid stimulating hormone (TSH), free thyroxin (FT4) and free triiodothyronine (FT3) were analyzed by electrochemiluminescence (E170, Roche Diagnostics). Serum ferritin was analyzed by immunochemiluminescence (Architect I2000, Abbott Laboratories). As ferritin levels decreased (>100, 30-100, 15-30, 100, 30-100, 15-30,
dc.identifier.doi10.1038/s41598-018-24352-9
dc.identifier.essn2045-2322
dc.identifier.pmcPMC5919900
dc.identifier.pmid29700318
dc.identifier.pubmedURLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919900/pdf
dc.identifier.unpaywallURLhttps://www.nature.com/articles/s41598-018-24352-9.pdf
dc.identifier.urihttp://hdl.handle.net/10668/12403
dc.issue.number1
dc.journal.titleScientific reports
dc.journal.titleabbreviationSci Rep
dc.language.isoen
dc.organizationHospital Universitario Virgen de la Victoria
dc.organizationHospital Universitario Virgen de la Victoria
dc.organizationHospital Universitario Regional de Málaga
dc.organizationHospital Universitario Regional de Málaga
dc.organizationInstituto de Investigación Biomédica de Málaga-IBIMA
dc.page.number6571
dc.pubmedtypeJournal Article
dc.pubmedtypeResearch Support, Non-U.S. Gov't
dc.rightsAttribution 4.0 International
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subject.meshAdolescent
dc.subject.meshAdult
dc.subject.meshAged
dc.subject.meshAged, 80 and over
dc.subject.meshAnemia, Iron-Deficiency
dc.subject.meshBiomarkers
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshHypothyroidism
dc.subject.meshMale
dc.subject.meshMiddle Aged
dc.subject.meshOdds Ratio
dc.subject.meshPopulation Surveillance
dc.subject.meshPrevalence
dc.subject.meshRisk Assessment
dc.subject.meshRisk Factors
dc.subject.meshSpain
dc.subject.meshThyroxine
dc.subject.meshTriiodothyronine
dc.subject.meshYoung Adult
dc.titleIron deficiency is associated with Hypothyroxinemia and Hypotriiodothyroninemia in the Spanish general adult population: Di@bet.es study.
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number8
dspace.entity.typePublication

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