Publication: Iron deficiency is associated with Hypothyroxinemia and Hypotriiodothyroninemia in the Spanish general adult population: Di@bet.es study.
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2018-04-26
Authors
Maldonado-Araque, Cristina
Valdés, Sergio
Lago-Sampedro, Ana
Lillo-Muñoz, Juan Antonio
Garcia-Fuentes, Eduardo
Perez-Valero, Vidal
Gutierrez-Repiso, Carolina
Goday, Albert
Urrutia, Ines
Peláez, Laura
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Abstract
Previous studies have suggested that iron deficiency (ID) may impair thyroid hormone metabolism, however replication in wide samples of the general adult population has not been performed. We studied 3846 individuals free of thyroid disease, participants in a national, cross sectional, population based study representative of the Spanish adult population. Thyroid stimulating hormone (TSH), free thyroxin (FT4) and free triiodothyronine (FT3) were analyzed by electrochemiluminescence (E170, Roche Diagnostics). Serum ferritin was analyzed by immunochemiluminescence (Architect I2000, Abbott Laboratories). As ferritin levels decreased (>100, 30-100, 15-30, 100, 30-100, 15-30,
Description
MeSH Terms
Adolescent
Adult
Aged
Aged, 80 and over
Anemia, Iron-Deficiency
Biomarkers
Female
Humans
Hypothyroidism
Male
Middle Aged
Odds Ratio
Population Surveillance
Prevalence
Risk Assessment
Risk Factors
Spain
Thyroxine
Triiodothyronine
Young Adult
Adult
Aged
Aged, 80 and over
Anemia, Iron-Deficiency
Biomarkers
Female
Humans
Hypothyroidism
Male
Middle Aged
Odds Ratio
Population Surveillance
Prevalence
Risk Assessment
Risk Factors
Spain
Thyroxine
Triiodothyronine
Young Adult