Publication: Plant catalases as NO and H2S targets
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Identifiers
Date
2020-05-25
Authors
Palma, José M.
Mateos, Rosa M.
López-Jaramillo, Javier
Rodríguez-Ruiz, Marta
González-Gordo, Salvador
Lechuga-Sancho, Alfonso M.
Corpas, Francisco J.
Advisors
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier
Abstract
Catalase is a powerful antioxidant metalloenzyme located in peroxisomes which also plays a central role in signaling processes under physiological and adverse situations. Whereas animals contain a single catalase gene, in plants this enzyme is encoded by a multigene family providing multiple isoenzymes whose number varies depending on the species, and their expression is regulated according to their tissue/organ distribution and the environmental conditions. This enzyme can be modulated by reactive oxygen and nitrogen species (ROS/RNS) as well as by hydrogen sulfide (H2S). Catalase is the major protein undergoing Tyr-nitration [post-translational modification (PTM) promoted by RNS] during fruit ripening, but the enzyme from diverse sources is also susceptible to undergo other activity-modifying PTMs. Data on S-nitrosation and persulfidation of catalase from different plant origins are given and compared here with results from obese children where S-nitrosation of catalase occurs. The cysteine residues prone to be S-nitrosated in catalase from plants and from bovine liver have been identified. These evidences assign to peroxisomes a crucial statement in the signaling crossroads among relevant molecules (NO and H2S), since catalase is allocated in these organelles. This review depicts a scenario where the regulation of catalase through PTMs, especially S-nitrosation and persulfidation, is highlighted.
Description
MeSH Terms
Medical Subject Headings::Organisms::Eukaryota::Animals
Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Oxidoreductases::Peroxidases::Catalase
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Artiodactyla::Ruminants::Cattle
Medical Subject Headings::Persons::Persons::Age Groups::Child
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Nitrogen Compounds::Nitrogen Oxides::Nitric Oxide
Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Cytoplasmic Vesicles::Cytoplasmic Granules::Microbodies::Peroxisomes
Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Nitrogen Compounds::Reactive Nitrogen Species
Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Acids::Acids, Noncarboxylic::Hydrogen Sulfide
Medical Subject Headings::Organisms::Eukaryota::Plants
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models, Theoretical::Models, Molecular::Molecular Docking Simulation
Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Oxidoreductases::Peroxidases::Catalase
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Artiodactyla::Ruminants::Cattle
Medical Subject Headings::Persons::Persons::Age Groups::Child
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Nitrogen Compounds::Nitrogen Oxides::Nitric Oxide
Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Cytoplasmic Vesicles::Cytoplasmic Granules::Microbodies::Peroxisomes
Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Nitrogen Compounds::Reactive Nitrogen Species
Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Acids::Acids, Noncarboxylic::Hydrogen Sulfide
Medical Subject Headings::Organisms::Eukaryota::Plants
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models, Theoretical::Models, Molecular::Molecular Docking Simulation
DeCS Terms
CIE Terms
Keywords
Docking, Nitration, S-nitrosation, Persulfidation, Post-translational modifications, Signaling, Nitración, Simulación del acoplamiento molecular, Nitrosación, Procesamiento proteico-postraduccional, Sulfuro de hidrógeno
Citation
Palma JM, Mateos RM, López-Jaramillo J, Rodríguez-Ruiz M, González-Gordo S, Lechuga-Sancho AM, et al. Plant catalases as NO and H2S targets. Redox Biol. 2020 Jul;34:101525