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Low-risk polycythemia vera treated with phlebotomies: clinical characteristics, hematologic control and complications in 453 patients from the Spanish Registry of Polycythemia Vera.

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dc.contributor.authorTriguero, Ana
dc.contributor.authorPedraza, Alexandra
dc.contributor.authorPérez-Encinas, Manuel
dc.contributor.authorMata-Vázquez, María Isabel
dc.contributor.authorVélez, Patricia
dc.contributor.authorFox, Laura
dc.contributor.authorGómez-Calafat, Montse
dc.contributor.authorGarcía-Delgado, Regina
dc.contributor.authorGasior, Mercedes
dc.contributor.authorFerrer-Marín, Francisca
dc.contributor.authorGarcía-Gutiérrez, Valentín
dc.contributor.authorAngona, Anna
dc.contributor.authorGómez-Casares, María Teresa
dc.contributor.authorCuevas, Beatriz
dc.contributor.authorMartínez, Clara
dc.contributor.authorPérez, Raúl
dc.contributor.authorRaya, José María
dc.contributor.authorGuerrero, Lucía
dc.contributor.authorMurillo, Ilda
dc.contributor.authorBellosillo, Beatriz
dc.contributor.authorHernández-Boluda, Juan Carlos
dc.contributor.authorSanz, Cristina
dc.contributor.authorÁlvarez-Larrán, Alberto
dc.contributor.authorOn behalf of the MPN Spanish Group (GEMFIN)
dc.date.accessioned2023-05-03T13:27:12Z
dc.date.available2023-05-03T13:27:12Z
dc.date.issued2022-08-30
dc.description.abstractHematological control, incidence of complications, and need for cytoreduction were studied in 453 patients with low-risk polycythemia vera (PV) treated with phlebotomies alone. Median hematocrit value decreased from 54% at diagnosis to 45% at 12 months, and adequate hematocrit control over time ( 60 years, and microvascular symptoms constituted the main indications for starting cytoreduction. Median duration without initiating cytoreduction was significantly longer in patients younger than 50 years (
dc.identifier.doi10.1007/s00277-022-04963-z
dc.identifier.essn1432-0584
dc.identifier.pmcPMC9584989
dc.identifier.pmid36042023
dc.identifier.pubmedURLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584989/pdf
dc.identifier.unpaywallURLhttps://link.springer.com/content/pdf/10.1007/s00277-022-04963-z.pdf
dc.identifier.urihttp://hdl.handle.net/10668/19719
dc.issue.number10
dc.journal.titleAnnals of hematology
dc.journal.titleabbreviationAnn Hematol
dc.language.isoen
dc.organizationHospital Universitario Virgen de la Victoria
dc.organizationHospital Costa del Sol
dc.page.number2231-2239
dc.pubmedtypeJournal Article
dc.rightsAttribution 4.0 International
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectLow-risk
dc.subjectMyelofibrosis
dc.subjectPhlebotomies
dc.subjectPolycythemia vera
dc.subjectThrombosis
dc.subject.meshHumans
dc.subject.meshLeukemia, Myeloid, Acute
dc.subject.meshMiddle Aged
dc.subject.meshPhlebotomy
dc.subject.meshPolycythemia Vera
dc.subject.meshPrimary Myelofibrosis
dc.subject.meshRegistries
dc.subject.meshThrombosis
dc.titleLow-risk polycythemia vera treated with phlebotomies: clinical characteristics, hematologic control and complications in 453 patients from the Spanish Registry of Polycythemia Vera.
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number101
dspace.entity.typePublication

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