Publication: Low-risk polycythemia vera treated with phlebotomies: clinical characteristics, hematologic control and complications in 453 patients from the Spanish Registry of Polycythemia Vera.
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2022-08-30
Authors
Triguero, Ana
Pedraza, Alexandra
Pérez-Encinas, Manuel
Mata-Vázquez, María Isabel
Vélez, Patricia
Fox, Laura
Gómez-Calafat, Montse
García-Delgado, Regina
Gasior, Mercedes
Ferrer-Marín, Francisca
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Abstract
Hematological control, incidence of complications, and need for cytoreduction were studied in 453 patients with low-risk polycythemia vera (PV) treated with phlebotomies alone. Median hematocrit value decreased from 54% at diagnosis to 45% at 12 months, and adequate hematocrit control over time ( 60 years, and microvascular symptoms constituted the main indications for starting cytoreduction. Median duration without initiating cytoreduction was significantly longer in patients younger than 50 years (
Description
MeSH Terms
Humans
Leukemia, Myeloid, Acute
Middle Aged
Phlebotomy
Polycythemia Vera
Primary Myelofibrosis
Registries
Thrombosis
Leukemia, Myeloid, Acute
Middle Aged
Phlebotomy
Polycythemia Vera
Primary Myelofibrosis
Registries
Thrombosis
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Keywords
Low-risk, Myelofibrosis, Phlebotomies, Polycythemia vera, Thrombosis