Publication: The Role of Left Atrial Longitudinal Strain in the Diagnosis of Acute Cellular Rejection in Heart Transplant Recipients.
Loading...
Identifiers
Date
2022-08-25
Authors
Rodríguez-Diego, Sara
Ruiz-Ortiz, Martín
Delgado-Ortega, Mónica
Kim, Jiwon
Weinsaft, Jonathan W
Sánchez-Fernández, José J
Ortega-Salas, Rosa
Carnero-Montoro, Lucía
Carrasco-Ávalos, Francisco
López-Aguilera, José
Advisors
Journal Title
Journal ISSN
Volume Title
Publisher
Metrics
Export
Abstract
Our aim was to investigate the role of left atrial longitudinal strain (LALS) in the non-invasive diagnosis of acute cellular rejection (ACR) episodes in heart transplant (HTx) recipients. Methods: We performed successive echocardiographic exams in 18 consecutive adult HTx recipients in their first year after HTx within 3 h of the routine surveillance endomyocardial biopsies (EMB) in a single center. LALS parameters were analyzed with two different software. We investigated LALS association with ACR presence, as well as inter-vendor variability in comparable LALS values. Results: A total of 147 pairs of EMB and echo exams were carried out. Lower values of LALS were significantly associated with any grade of ACR presence. Peak atrial longitudinal strain (PALS) offered the best diagnostic value for any grade of ACR, with a C statistic of 0.77 using one software (95% CI 0.68−0.84, p
Description
MeSH Terms
DeCS Terms
CIE Terms
Keywords
heart transplantation, left atrial strain, rejection, speckle-tracking echocardiography