RT Journal Article T1 The Role of Left Atrial Longitudinal Strain in the Diagnosis of Acute Cellular Rejection in Heart Transplant Recipients. A1 Rodríguez-Diego, Sara A1 Ruiz-Ortiz, Martín A1 Delgado-Ortega, Mónica A1 Kim, Jiwon A1 Weinsaft, Jonathan W A1 Sánchez-Fernández, José J A1 Ortega-Salas, Rosa A1 Carnero-Montoro, Lucía A1 Carrasco-Ávalos, Francisco A1 López-Aguilera, José A1 López-Granados, Amador A1 Arizón Del Prado, José M A1 Romo-Peñas, Elías A1 Pardo-González, Laura A1 Hidalgo-Lesmes, Francisco J A1 Álvarez-Ossorio, Manuel Pan A1 Mesa-Rubio, Dolores K1 heart transplantation K1 left atrial strain K1 rejection K1 speckle-tracking echocardiography AB Our aim was to investigate the role of left atrial longitudinal strain (LALS) in the non-invasive diagnosis of acute cellular rejection (ACR) episodes in heart transplant (HTx) recipients. Methods: We performed successive echocardiographic exams in 18 consecutive adult HTx recipients in their first year after HTx within 3 h of the routine surveillance endomyocardial biopsies (EMB) in a single center. LALS parameters were analyzed with two different software. We investigated LALS association with ACR presence, as well as inter-vendor variability in comparable LALS values. Results: A total of 147 pairs of EMB and echo exams were carried out. Lower values of LALS were significantly associated with any grade of ACR presence. Peak atrial longitudinal strain (PALS) offered the best diagnostic value for any grade of ACR, with a C statistic of 0.77 using one software (95% CI 0.68−0.84, p SN 2077-0383 YR 2022 FD 2022-08-25 LK http://hdl.handle.net/10668/21337 UL http://hdl.handle.net/10668/21337 LA en DS RISalud RD Apr 14, 2025