Publication: Hospital and outpatient models for Hematopoietic Stem Cell Transplantation: A systematic review of comparative studies for health outcomes, experience of care and costs.
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Date
2021-08-12
Authors
González, Marino J
Urizar, Elena
Urtaran-Laresgoiti, Maider
Nuño-Solinís, Roberto
Lázaro-Pérez, Esther
Vázquez, Lourdes
Pascual-Cascón, Maria Jesús
Solano, Carlos
Kwon, Mi
Gallego, Cristina
Advisors
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Abstract
The number of Hematopoietic Stem Cell Transplantations has risen in the past 20 years. The practice of outpatient Hematopoietic Stem Cell Transplantation programs is increasing in an attempt to improve the quality of patient care and reduce the demand for hospital admission. A systematic review of 29 comparative studies between in-hospital and outpatient treatment of Hematopoietic Stem Cell Transplantation, with no restriction by outpatient regime was conducted. This study aims to analyse the current evidence on the effects of the outpatient model on patient-centred outcomes, comparing both in-hospital and outpatient models for autologous and allogeneic HSCT using the Triple Aim framework: health outcomes, costs and experience of care. We found evidence on improved health outcomes and quality of life, on enhanced safety and effectiveness and on reduced overall costs and hospital stays, with similar results on overall survival rates comparing both models for autologous and allogeneic patients. We also found that the outpatient Hematopoietic Stem Cell Transplantation is a safe practice as well as less costly, it requires fewer days of hospital stay both for autologous and allogeneic transplantations. Under a situation of an increasing number of transplants, rising healthcare costs and shortages of hospital capacity, incorporating outpatient models could improve the quality of care for people requiring Hematopoietic Stem Cell Transplantation programs.
Description
MeSH Terms
Costs and Cost Analysis
Disease-Free Survival
Hematopoietic Stem Cell Transplantation
Humans
Length of Stay
Models, Economic
Quality of Life
Survival Rate
Transplantation, Autologous
Transplantation, Homologous
Disease-Free Survival
Hematopoietic Stem Cell Transplantation
Humans
Length of Stay
Models, Economic
Quality of Life
Survival Rate
Transplantation, Autologous
Transplantation, Homologous