RT Journal Article
T1 Hospital and outpatient models for Hematopoietic Stem Cell Transplantation: A systematic review of comparative studies for health outcomes, experience of care and costs.
A1 Gonzalez, Marino J
A1 Urizar, Elena
A1 Urtaran-Laresgoiti, Maider
A1 Nuño-Solinis, Roberto
A1 Lazaro-Perez, Esther
A1 Vazquez, Lourdes
A1 Pascual-Cascon, Maria Jesus
A1 Solano, Carlos
A1 Kwon, Mi
A1 Gallego, Cristina
A1 Fernandez-Aviles, Francesc
K1 Quality of Life
K1 Survival Rate
K1 Transplantation, Autologous
K1 Transplantation, Homologous
AB The number of Hematopoietic Stem Cell Transplantations has risen in the past 20 years. The practice of outpatient Hematopoietic Stem Cell Transplantation programs is increasing in an attempt to improve the quality of patient care and reduce the demand for hospital admission. A systematic review of 29 comparative studies between in-hospital and outpatient treatment of Hematopoietic Stem Cell Transplantation, with no restriction by outpatient regime was conducted. This study aims to analyse the current evidence on the effects of the outpatient model on patient-centred outcomes, comparing both in-hospital and outpatient models for autologous and allogeneic HSCT using the Triple Aim framework: health outcomes, costs and experience of care. We found evidence on improved health outcomes and quality of life, on enhanced safety and effectiveness and on reduced overall costs and hospital stays, with similar results on overall survival rates comparing both models for autologous and allogeneic patients. We also found that the outpatient Hematopoietic Stem Cell Transplantation is a safe practice as well as less costly, it requires fewer days of hospital stay both for autologous and allogeneic transplantations. Under a situation of an increasing number of transplants, rising healthcare costs and shortages of hospital capacity, incorporating outpatient models could improve the quality of care for people requiring Hematopoietic Stem Cell Transplantation programs.
PB Public Library of Science
YR 2021
FD 2021-08-12
LK http://hdl.handle.net/10668/18363
UL http://hdl.handle.net/10668/18363
LA en
NO González MJ, Urizar E, Urtaran-Laresgoiti M, Nuño-Solinís R, Lázaro-Pérez E, Vázquez L, et al. Hospital and outpatient models for Hematopoietic Stem Cell Transplantation: A systematic review of comparative studies for health outcomes, experience of care and costs. PLoS One. 2021 Aug 12;16(8):e0254135
DS RISalud
RD Apr 11, 2025