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Anti-Inflammatory Effects of the Mediterranean Diet in the Early and Late Stages of Atheroma Plaque Development

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dc.contributor.authorCasas, Rosa
dc.contributor.authorUrpi-Sarda, Mireia
dc.contributor.authorSacanella, Emilio
dc.contributor.authorArranz, Sara
dc.contributor.authorCorella, Dolores
dc.contributor.authorCastaner, Olga
dc.contributor.authorLamuela-Raventos, Rosa-Maria
dc.contributor.authorSalas-Salvado, Jordi
dc.contributor.authorLapetra, Jose
dc.contributor.authorPortillo, Maria P.
dc.contributor.authorEstruch, Ramon
dc.contributor.authoraffiliation[Casas, Rosa] Univ Barcelona, Hosp Clin, Inst Invest Biomed August Pi & Sunyer IDIBAPS, Villarroel 170, E-08036 Barcelona, Spain
dc.contributor.authoraffiliation[Sacanella, Emilio] Univ Barcelona, Hosp Clin, Inst Invest Biomed August Pi & Sunyer IDIBAPS, Villarroel 170, E-08036 Barcelona, Spain
dc.contributor.authoraffiliation[Arranz, Sara] Univ Barcelona, Hosp Clin, Inst Invest Biomed August Pi & Sunyer IDIBAPS, Villarroel 170, E-08036 Barcelona, Spain
dc.contributor.authoraffiliation[Estruch, Ramon] Univ Barcelona, Hosp Clin, Inst Invest Biomed August Pi & Sunyer IDIBAPS, Villarroel 170, E-08036 Barcelona, Spain
dc.contributor.authoraffiliation[Casas, Rosa] Inst Salud Carlos III, Ciber Fisiopatol Obesidad & Nutr CIBEROBN, Madrid, Spain
dc.contributor.authoraffiliation[Sacanella, Emilio] Inst Salud Carlos III, Ciber Fisiopatol Obesidad & Nutr CIBEROBN, Madrid, Spain
dc.contributor.authoraffiliation[Arranz, Sara] Inst Salud Carlos III, Ciber Fisiopatol Obesidad & Nutr CIBEROBN, Madrid, Spain
dc.contributor.authoraffiliation[Corella, Dolores] Inst Salud Carlos III, Ciber Fisiopatol Obesidad & Nutr CIBEROBN, Madrid, Spain
dc.contributor.authoraffiliation[Castaner, Olga] Inst Salud Carlos III, Ciber Fisiopatol Obesidad & Nutr CIBEROBN, Madrid, Spain
dc.contributor.authoraffiliation[Lamuela-Raventos, Rosa-Maria] Inst Salud Carlos III, Ciber Fisiopatol Obesidad & Nutr CIBEROBN, Madrid, Spain
dc.contributor.authoraffiliation[Salas-Salvado, Jordi] Inst Salud Carlos III, Ciber Fisiopatol Obesidad & Nutr CIBEROBN, Madrid, Spain
dc.contributor.authoraffiliation[Lapetra, Jose] Inst Salud Carlos III, Ciber Fisiopatol Obesidad & Nutr CIBEROBN, Madrid, Spain
dc.contributor.authoraffiliation[Portillo, Maria P.] Inst Salud Carlos III, Ciber Fisiopatol Obesidad & Nutr CIBEROBN, Madrid, Spain
dc.contributor.authoraffiliation[Estruch, Ramon] Inst Salud Carlos III, Ciber Fisiopatol Obesidad & Nutr CIBEROBN, Madrid, Spain
dc.contributor.authoraffiliation[Urpi-Sarda, Mireia] Univ Barcelona, Sch Pharm, Dept Nutr & Food Sci, Av Joan XXIII S-N, E-08028 Barcelona, Spain
dc.contributor.authoraffiliation[Lamuela-Raventos, Rosa-Maria] Univ Barcelona, Sch Pharm, Dept Nutr & Food Sci, Av Joan XXIII S-N, E-08028 Barcelona, Spain
dc.contributor.authoraffiliation[Corella, Dolores] Univ Valencia, Sch Med, Dept Epidemiol, Valencia, Spain
dc.contributor.authoraffiliation[Corella, Dolores] Univ Valencia, Sch Med, Dept Biochem & Mol Biol, Valencia, Spain
dc.contributor.authoraffiliation[Castaner, Olga] Hosp Mar Med Res Inst IMIM, Cardiovasc Risk & Nutr & REGICOR Res Grp, Barcelona, Spain
dc.contributor.authoraffiliation[Salas-Salvado, Jordi] Univ Rovira & Virgili, Hosp Univ Sant Joan Reus, IISPV, Human Nutr Unit, Reus, Spain
dc.contributor.authoraffiliation[Lapetra, Jose] Distrito Sanitario Atenc Primaria Sevilla, Dept Family Med, Res Unit, Seville, Spain
dc.contributor.authoraffiliation[Portillo, Maria P.] Univ Basque Country, UPV EHU, Lucio Lascaray Res Ctr, Dept Nutr & Food Sci,Nutr & Obes Grp, Vitoria, Spain
dc.contributor.funderInstituto de Salud Carlos III, Spain
dc.contributor.funder"Ramon y Cajal" program of MINECO
dc.contributor.funderFondo Social Europeo
dc.date.accessioned2023-02-12T02:21:50Z
dc.date.available2023-02-12T02:21:50Z
dc.date.issued2017-01-01
dc.description.abstractObjective. To evaluate the long-term effects of a Mediterranean diet (MeDiet) intervention on the plasma concentrations of inflammatory and plaque stability-related molecules in elderly people at high risk for cardiovascular disease. Design and Setting. 66 participants from primary care centers affiliated with the Hospital Clinic of Barcelona were randomized into 3 groups: MeDiet plus extra virgin olive oil (EVOO) or nuts and a low-fat diet (LFD). At baseline and at 3 and 5 years, we evaluated the changes in the plasma concentrations of 24 inflammatory biomarkers related to the different stages of the atherosclerotic process by Luminex (R). Results. At 3 and 5 years, both MeDiet groups showed a significant reduction of IL-6, IL-8, MCP-1, and MIP-1 beta (P
dc.identifier.doi10.1155/2017/3674390
dc.identifier.essn1466-1861
dc.identifier.issn0962-9351
dc.identifier.unpaywallURLhttp://downloads.hindawi.com/journals/mi/2017/3674390.pdf
dc.identifier.urihttp://hdl.handle.net/10668/19055
dc.identifier.wosID399496900001
dc.journal.titleMediators of inflammation
dc.journal.titleabbreviationMediat. inflamm.
dc.language.isoen
dc.organizationSevilla
dc.publisherHindawi ltd
dc.rightsAttribution 4.0 International
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectLow-grade inflammation
dc.subjectCardiovascular-disease
dc.subjectHigh-risk
dc.subjectMarkers
dc.subjectAtherosclerosis
dc.subjectActivation
dc.subjectCytokines
dc.subjectPattern
dc.titleAnti-Inflammatory Effects of the Mediterranean Diet in the Early and Late Stages of Atheroma Plaque Development
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number2017
dc.wostypeArticle
dspace.entity.typePublication

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