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Incidence, clinical, risk factors and outcomes of Guillain-Barré in Covid-19.

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dc.contributor.authorFragiel, Marcos
dc.contributor.authorMiro, Oscar
dc.contributor.authorLlorens, Pere
dc.contributor.authorJimenez, Sonia
dc.contributor.authorPiñera, Pascual
dc.contributor.authorBurillo, Guillermo
dc.contributor.authorMartin, Alfonso
dc.contributor.authorMartin-Sanchez, Francisco J
dc.contributor.authorGarcia-Lamberechts, Eric J
dc.contributor.authorJacob, Javier
dc.contributor.authorAlquezar-Arbe, Aitor
dc.contributor.authorJuarez, Ricardo
dc.contributor.authorJimenez, Blas
dc.contributor.authorDel Rio, Rigoberto
dc.contributor.authorMateo Roca, Miriam
dc.contributor.authorGarcia, Arturo H
dc.contributor.authorLopez Laguna, Nieves
dc.contributor.authorLopez Diez, Maria P
dc.contributor.authorPedraza Garcia, Jorge
dc.contributor.authorFernandez de Simon Almela, Amparo
dc.contributor.authorLopez Diaz, Juan J
dc.contributor.authorEiroa Hernandez, Patricia
dc.contributor.authorRuiz de Lobera, Noemi
dc.contributor.authorPorta-Etessam, Jesus
dc.contributor.authorFernandez Perez, Cristina
dc.contributor.authorCalvo, Elpidio
dc.contributor.authorGonzalez Del Castillo, Juan
dc.contributor.groupSIESTA (Spanish Investigators in Emergency Situations Team) network
dc.date.accessioned2023-02-09T10:38:09Z
dc.date.available2023-02-09T10:38:09Z
dc.date.issued2020-12-09
dc.description.abstractWe diagnosed 11 Guillain-Barré syndrome (GBS) cases among 71,904 COVID patients attended at 61 Spanish emergency departments (EDs) during the 2-month pandemic peak. The relative frequency of GBS among ED patients was higher in COVID (0.15‰) than non-COVID (0.02‰) patients (odds ratio [OR] = 6.30, 95% confidence interval [CI] = 3.18-12.5), as was the standardized incidence (9.44 and 0.69 cases/100,000 inhabitant-years, respectively, OR = 13.5, 95% CI = 9.87-18.4). Regarding clinical characteristics, olfactory-gustatory disorders were more frequent in COVID-GBS than non-COVID-GBS (OR = 27.59, 95% CI = 1.296-587) and COVID-non-GBS (OR = 7.875, 95% CI = 1.587-39.09) patients. Although COVID-GBS patients were more frequently admitted to intensive care, mortality was not increased versus control groups. Our results suggest SARS-CoV-2 could be another viral infection causing GBS. ANN NEUROL 2021;89:598-603.
dc.description.versionSi
dc.identifier.citationFragiel M, Miró Ò, Llorens P, Jiménez S, Piñera P, Burillo G, et al. Incidence, clinical, risk factors and outcomes of Guillain-Barré in Covid-19. Ann Neurol. 2021 Mar;89(3):598-603.
dc.identifier.doi10.1002/ana.25987
dc.identifier.essn1531-8249
dc.identifier.pmid33295021
dc.identifier.urihttp://hdl.handle.net/10668/16761
dc.issue.number3
dc.journal.titleAnnals of neurology
dc.journal.titleabbreviationAnn Neurol
dc.language.isoen
dc.organizationIMIBIC
dc.page.number598-603
dc.publisherJohn Wiley & Sons, Inc.
dc.pubmedtypeJournal Article
dc.relation.publisherversionhttps://doi.org/10.1002/ana.25987
dc.rights.accessRightsopen access
dc.subjectAdult
dc.subjectAged
dc.subjectCOVID-19
dc.subjectCase-Control Studies
dc.subjectFemale
dc.subjectGuillain-Barre Syndrome
dc.subjectHospital Mortality
dc.subjectHumans
dc.subject.decsEspaña
dc.subject.decsFactores inmunológicos
dc.subject.decsFactores de riesgo
dc.subject.decsIncidencia
dc.subject.decsInmunoglobulinas intravenosas
dc.subject.decsMasculino
dc.subject.decsTiempo de internación
dc.subject.decsTrastornos del gusto
dc.subject.decsTrastornos del olfato
dc.subject.decsUnidades de cuidados intensivos
dc.subject.meshImmunoglobulins, Intravenous
dc.subject.meshImmunologic Factors
dc.subject.meshIncidence
dc.subject.meshIntensive Care Units
dc.subject.meshLength of Stay
dc.subject.meshMale
dc.subject.meshMiddle Aged
dc.subject.meshOlfaction Disorders
dc.subject.meshRisk Factors
dc.subject.meshSARS-CoV-2
dc.subject.meshSpain
dc.subject.meshTaste Disorders
dc.titleIncidence, clinical, risk factors and outcomes of Guillain-Barré in Covid-19.
dc.typeresearch article
dc.volume.number89
dspace.entity.typePublication

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