Publication: Inmunopatología de la esclerosis múltiple.
| dc.contributor.author | Quintana, Francisco J. | |
| dc.contributor.author | Pérez-Sánchez, Soledad | |
| dc.contributor.author | Farez, Mauricio F. | |
| dc.contributor.authoraffiliation | [Quintana,FJ] Center for Neurologic Diseases, Department of Neurology, Brigham and Women’s Hospital, Harvard Medical School, Boston, USA. [Pérez-Sánchez,S] Unidad de Esclerosis Múltiple, Hospital Universitario Virgen Macarena, Sevilla, España. [Farez,MF] Instituto de Investigaciones Neurológicas Dr. Raúl Carrea, FLENI, Buenos Aires, Argentina. | es |
| dc.date.accessioned | 2016-05-24T09:21:54Z | |
| dc.date.available | 2016-05-24T09:21:54Z | |
| dc.date.issued | 2014 | |
| dc.description | English Abstract; Journal Article; Review; | es |
| dc.description.abstract | La esclerosis múltiple es una enfermedad inflamatoria desmielinizante que afecta el sistema nervioso central y que es considerada una de las principales causas de discapacidad en jóvenes adultos. Las causas de la esclerosis múltiple son aún desconocidas, aunque se cree que una combinación de factores genéticos y ambientales resulta en una respuesta autoinmune que promueve la degeneración neuronal/axonal. En esta revisión se analiza la asociación entre la respuesta inmune y la neurodegeneración en la esclerosis múltiple. | es_ES |
| dc.description.abstract | Multiple sclerosis is an inflammatory demyelinating disease affecting the central nervous system and considered one of the leading causes of disability in young adults. The precise cause of multiple sclerosis is unknown, although the current evidence points towards a combination of genetic and environmental factors leading to an autoimmune response that promotes neuronal degeneration. In this review, we will describe the association between the immune response and neurodegeneration in multiple sclerosis. | es_ES |
| dc.description.version | Yes | es |
| dc.identifier.citation | Quintana FJ, Pérez-Sánchez S, Farez MF. Inmunopatología de la esclerosis múltiple. Medicina (B Aires). 2014; 74(5):404-10 | es |
| dc.identifier.essn | 1669-9106 | |
| dc.identifier.issn | 0025-7680 | |
| dc.identifier.pmid | 25347906 | |
| dc.identifier.uri | http://hdl.handle.net/10668/2200 | |
| dc.journal.title | Medicina (Buenos Aires) | |
| dc.language.iso | spa | |
| dc.publisher | Fundación Revista Medicina | es |
| dc.relation.publisherversion | http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0025-76802014000500012 | es |
| dc.rights.accessRights | open access | |
| dc.subject | Multiple sclerosis | es |
| dc.subject | Pathogenesis | es |
| dc.subject | Esclerosis múltiple | es |
| dc.subject | Patogénesis | es |
| dc.subject | Enfermedades neurodegenerativas | es |
| dc.subject | Inmunidad celular | es |
| dc.subject | Vaina de mielina | es |
| dc.subject.mesh | Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans | es |
| dc.subject.mesh | Medical Subject Headings::Phenomena and Processes::Immune System Phenomena::Immunity::Adaptive Immunity::Immunity, Cellular | es |
| dc.subject.mesh | Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Inflammation | es |
| dc.subject.mesh | Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Macrophages | es |
| dc.subject.mesh | Medical Subject Headings::Diseases::Immune System Diseases::Autoimmune Diseases::Autoimmune Diseases of the Nervous System::Demyelinating Autoimmune Diseases, CNS::Multiple Sclerosis | es |
| dc.subject.mesh | Medical Subject Headings::Anatomy::Nervous System::Neuroglia::Oligodendroglia::Myelin Sheath | es |
| dc.subject.mesh | Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Nerve Degeneration | es |
| dc.subject.mesh | Medical Subject Headings::Diseases::Nervous System Diseases::Neurodegenerative Diseases | es |
| dc.subject.mesh | Medical Subject Headings::Anatomy::Nervous System::Neuroglia | es |
| dc.subject.mesh | Medical Subject Headings::Anatomy::Cells::Blood Cells::Leukocytes::Leukocytes, Mononuclear::Cytokine-Induced Killer Cells::T-Lymphocytes, Cytotoxic | es |
| dc.subject.mesh | Medical Subject Headings::Anatomy::Hemic and Immune Systems::Immune System::Antibody-Producing Cells::B-Lymphocytes | es |
| dc.title | Inmunopatología de la esclerosis múltiple. | es |
| dc.title | Immunopathology of multiple sclerosis | es |
| dc.type | research article | |
| dc.type.hasVersion | VoR | |
| dspace.entity.type | Publication |
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