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Melatonin-doped polymeric nanoparticles induce high crystalline apatite formation in root dentin

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dc.contributor.authorToledano-Osorio, Manuel
dc.contributor.authorAguilera, Fatima S.
dc.contributor.authorMunoz-Soto, Esther
dc.contributor.authorOsorio, Estrella
dc.contributor.authorToledano, Manuel
dc.contributor.authorEscames, Germaine
dc.contributor.authorMedina-Castillo, Antonio L.
dc.contributor.authorOsorio, Maria T.
dc.contributor.authorLopez-Lopez, Modesto T.
dc.contributor.authorVallecillo-Rivas, Marta
dc.contributor.authorOsorio, Raquel
dc.contributor.authoraffiliation[Toledano-Osorio, Manuel] Univ Granada, Dept Stomatol, Colegio Maximo De Cartuja S-N, Granada 18071, Spain
dc.contributor.authoraffiliation[Aguilera, Fatima S.] Univ Granada, Dept Stomatol, Colegio Maximo De Cartuja S-N, Granada 18071, Spain
dc.contributor.authoraffiliation[Munoz-Soto, Esther] Univ Granada, Dept Stomatol, Colegio Maximo De Cartuja S-N, Granada 18071, Spain
dc.contributor.authoraffiliation[Osorio, Estrella] Univ Granada, Dept Stomatol, Colegio Maximo De Cartuja S-N, Granada 18071, Spain
dc.contributor.authoraffiliation[Toledano, Manuel] Univ Granada, Dept Stomatol, Colegio Maximo De Cartuja S-N, Granada 18071, Spain
dc.contributor.authoraffiliation[Vallecillo-Rivas, Marta] Univ Granada, Dept Stomatol, Colegio Maximo De Cartuja S-N, Granada 18071, Spain
dc.contributor.authoraffiliation[Osorio, Raquel] Univ Granada, Dept Stomatol, Colegio Maximo De Cartuja S-N, Granada 18071, Spain
dc.contributor.authoraffiliation[Escames, Germaine] Univ Granada, Ibs San Cecilio Univ Hosp, Fac Med, Biomed Res Ctr,Dept Physiol,CIBERFES, Granada, Spain
dc.contributor.authoraffiliation[Medina-Castillo, Antonio L.] Univ Granada, NanoMyP, Spin Off Enterprise, Edificio BIC Granada,Av Innovac 1, Granada 18016, Spain
dc.contributor.authoraffiliation[Lopez-Lopez, Modesto T.] Univ Granada, Fac Sci, Appl Phys Dept, Av Fuente Nueva S-N, Granada 18071, Spain
dc.contributor.funderMinistry of Economy and Competitiveness and European Regional Development Fund( MINECO/AEI/FEDER/UE)
dc.contributor.funderUniversity of Granada/CBUA
dc.date.accessioned2023-02-12T02:20:47Z
dc.date.available2023-02-12T02:20:47Z
dc.date.issued2021-11-03
dc.description.abstractObjective. To investigate the effect of novel polymeric nanoparticles (NPs) doped with melatonin (ML) on nano-hardness, crystallinity and ultrastructure of the formed hydroxyapatite after endodontic treatment. Methods. Undoped-NPs and ML-doped NPs (ML-NPs) were tested at radicular dentin, after 24 h and 6 m. A control group without NPs was included. Radicular cervical and apical dentin surfaces were studied by nano-hardness measurements, X-ray diffraction and transmission electron microscopy. Mean and standard deviation were analyzed by ANOVA and StudentNewman-Keuls multiple comparisons (p
dc.identifier.doi10.1016/j.dental.2021.09.001
dc.identifier.essn1879-0097
dc.identifier.issn0109-5641
dc.identifier.unpaywallURLhttps://doi.org/10.1016/j.dental.2021.09.001
dc.identifier.urihttp://hdl.handle.net/10668/18759
dc.identifier.wosID717973400009
dc.issue.number11
dc.journal.titleDental materials
dc.journal.titleabbreviationDent. mater.
dc.language.isoen
dc.organizationHospital Universitario San Cecilio
dc.organizationHospital Universitario San Cecilio
dc.page.number1698-1713
dc.publisherElsevier sci ltd
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectApatite
dc.subjectDentin
dc.subjectHardness
dc.subjectMelatonin
dc.subjectPolymeric nanoparticles
dc.subjectRemineralization
dc.subjectTransmission electron microscopy
dc.subjectX-ray diffraction
dc.subjectOxidative stress
dc.subjectCarious dentin
dc.subjectOrganic matrix
dc.subjectHydroxyapatite
dc.subjectBone
dc.subjectCements
dc.subjectRemineralization
dc.subjectMineralization
dc.subjectInterface
dc.subjectTexture
dc.titleMelatonin-doped polymeric nanoparticles induce high crystalline apatite formation in root dentin
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number37
dc.wostypeArticle
dspace.entity.typePublication

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