Publication:
Mycobacterium tuberculosis Acquires Limited Genetic Diversity in Prolonged Infections, Reactivations and Transmissions Involving Multiple Hosts

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dc.contributor.authorHerranz, Marta
dc.contributor.authorPole, Ilva
dc.contributor.authorOzere, Iveta
dc.contributor.authorChiner-Oms, Alvaro
dc.contributor.authorMartinez-Lirola, Miguel
dc.contributor.authorPerez-Garcia, Felipe
dc.contributor.authorGijon, Paloma
dc.contributor.authorRuiz Serrano, Maria Jesus
dc.contributor.authorClotet Romero, Laura
dc.contributor.authorCuevas, Oscar
dc.contributor.authorComas, Inaki
dc.contributor.authorBouza, Emilio
dc.contributor.authorPerez-Lago, Laura
dc.contributor.authorGarcia-de-Viedma, Dario
dc.contributor.authoraffiliation[Herranz, Marta] Hosp Gen Univ Gregorio Maranon, Serv Microbiol Clin & Enfermedades Infecciosas, Madrid, Spain
dc.contributor.authoraffiliation[Perez-Garcia, Felipe] Hosp Gen Univ Gregorio Maranon, Serv Microbiol Clin & Enfermedades Infecciosas, Madrid, Spain
dc.contributor.authoraffiliation[Gijon, Paloma] Hosp Gen Univ Gregorio Maranon, Serv Microbiol Clin & Enfermedades Infecciosas, Madrid, Spain
dc.contributor.authoraffiliation[Ruiz Serrano, Maria Jesus] Hosp Gen Univ Gregorio Maranon, Serv Microbiol Clin & Enfermedades Infecciosas, Madrid, Spain
dc.contributor.authoraffiliation[Bouza, Emilio] Hosp Gen Univ Gregorio Maranon, Serv Microbiol Clin & Enfermedades Infecciosas, Madrid, Spain
dc.contributor.authoraffiliation[Perez-Lago, Laura] Hosp Gen Univ Gregorio Maranon, Serv Microbiol Clin & Enfermedades Infecciosas, Madrid, Spain
dc.contributor.authoraffiliation[Garcia-de-Viedma, Dario] Hosp Gen Univ Gregorio Maranon, Serv Microbiol Clin & Enfermedades Infecciosas, Madrid, Spain
dc.contributor.authoraffiliation[Herranz, Marta] Inst Invest Sanit Gregorio Maranon, Madrid, Spain
dc.contributor.authoraffiliation[Perez-Garcia, Felipe] Inst Invest Sanit Gregorio Maranon, Madrid, Spain
dc.contributor.authoraffiliation[Gijon, Paloma] Inst Invest Sanit Gregorio Maranon, Madrid, Spain
dc.contributor.authoraffiliation[Ruiz Serrano, Maria Jesus] Inst Invest Sanit Gregorio Maranon, Madrid, Spain
dc.contributor.authoraffiliation[Bouza, Emilio] Inst Invest Sanit Gregorio Maranon, Madrid, Spain
dc.contributor.authoraffiliation[Perez-Lago, Laura] Inst Invest Sanit Gregorio Maranon, Madrid, Spain
dc.contributor.authoraffiliation[Garcia-de-Viedma, Dario] Inst Invest Sanit Gregorio Maranon, Madrid, Spain
dc.contributor.authoraffiliation[Herranz, Marta] CIBER Enfermedades Resp CIBERES, Madrid, Spain
dc.contributor.authoraffiliation[Gijon, Paloma] CIBER Enfermedades Resp CIBERES, Madrid, Spain
dc.contributor.authoraffiliation[Ruiz Serrano, Maria Jesus] CIBER Enfermedades Resp CIBERES, Madrid, Spain
dc.contributor.authoraffiliation[Bouza, Emilio] CIBER Enfermedades Resp CIBERES, Madrid, Spain
dc.contributor.authoraffiliation[Perez-Lago, Laura] CIBER Enfermedades Resp CIBERES, Madrid, Spain
dc.contributor.authoraffiliation[Garcia-de-Viedma, Dario] CIBER Enfermedades Resp CIBERES, Madrid, Spain
dc.contributor.authoraffiliation[Pole, Ilva] Riga East Univ Hosp, Ctr TB & Lung Dis, Childhood TB Dept, Riga, Latvia
dc.contributor.authoraffiliation[Ozere, Iveta] Riga East Univ Hosp, Ctr TB & Lung Dis, Childhood TB Dept, Riga, Latvia
dc.contributor.authoraffiliation[Pole, Ilva] Latvian Biomed Res & Study Ctr, Riga, Latvia
dc.contributor.authoraffiliation[Ozere, Iveta] Riga Stradins Univ, Dept Infectol & Dermatol, Riga, Latvia
dc.contributor.authoraffiliation[Chiner-Oms, Alvaro] Univ Valencia, Unidad Mixta Genom & Salud, Ctr Super Invest Salud Publ FISABIO, Valencia, Spain
dc.contributor.authoraffiliation[Martinez-Lirola, Miguel] Complejo Hosp Torrecardenas, Serv Microbiol, Almeria, Spain
dc.contributor.authoraffiliation[Clotet Romero, Laura] Agencia Salut Publ Catalunya, Subdireccio Gen Vigilancia & Resposta Emergencies, Serv Vigilancia Epidemiol & Resposta Emergencies, Barcelona, Spain
dc.contributor.authoraffiliation[Cuevas, Oscar] Univ Autonoma Barcelona, Parc Tauli Hosp Univ I3PT, Inst Invest & Innovacio Parc Tauli, Serv Lab, Barcelona, Spain
dc.contributor.authoraffiliation[Comas, Inaki] CSIC, Inst Biomed Valencia, Valencia, Spain
dc.contributor.authoraffiliation[Comas, Inaki] CIBER Epidemiol & Salud Publ, Madrid, Spain
dc.contributor.authoraffiliation[Bouza, Emilio] Univ Complutense Madrid, Fac Med, Dept Med, Madrid, Spain
dc.contributor.funderMinistry of Economy and Competitiveness ISCIII FIS
dc.contributor.funderERDF (FEDER) Funds from the European Commission: "A way of making Europe"
dc.contributor.funderLatvian National Research program VPP 5.7 "BIOMEDICINE"
dc.contributor.funderMinisterio de Educacion y Ciencia
dc.contributor.funderEuropean Research Council (ERC)
dc.contributor.funderMinisterio de Educacion y Ciencia (Spanish Government)
dc.date.accessioned2023-02-12T02:22:40Z
dc.date.available2023-02-12T02:22:40Z
dc.date.issued2018-01-19
dc.description.abstractBackground: Mycobacterium tuberculosis (MTB) has limited ability to acquire variability. Analysis of its microevolution might help us to evaluate the pathways followed to acquire greater infective success. Whole-genome sequencing (WGS) in the analysis of the transmission of MTB has elucidated the magnitude of variability in MTB. Analysis of transmission currently depends on the identification of clusters, according to the threshold of variability (
dc.identifier.doi10.3389/fmicb.2017.02661
dc.identifier.issn1664-302X
dc.identifier.unpaywallURLhttps://www.frontiersin.org/articles/10.3389/fmicb.2017.02661/pdf
dc.identifier.urihttp://hdl.handle.net/10668/19225
dc.identifier.wosID422951200001
dc.journal.titleFrontiers in microbiology
dc.journal.titleabbreviationFront. microbiol.
dc.language.isoen
dc.organizationHospital Torrecárdenas
dc.publisherFrontiers media sa
dc.rightsAttribution 4.0 International
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjecttuberculosis
dc.subjectvariability
dc.subjectwhole genome sequencing
dc.subjectSNPs
dc.subjectmicroevolution
dc.subjectClonal variants
dc.subjectMicroevolution
dc.subjectOutbreaks
dc.subjectStrain
dc.subjectAfrica
dc.titleMycobacterium tuberculosis Acquires Limited Genetic Diversity in Prolonged Infections, Reactivations and Transmissions Involving Multiple Hosts
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number8
dc.wostypeArticle
dspace.entity.typePublication

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