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Evaluation of the Kinetics of Antibody Response to COVID-19 Vaccine in Solid Organ Transplant Recipients: The Prospective Multicenter ORCHESTRA Cohort.

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dc.contributor.authorGiannella, Maddalena
dc.contributor.authorRighi, Elda
dc.contributor.authorPascale, Renato
dc.contributor.authorRinaldi, Matteo
dc.contributor.authorCaroccia, Natascia
dc.contributor.authorGamberini, Chiara
dc.contributor.authorPalacios-Baena, Zaira R
dc.contributor.authorCaponcello, Giulia
dc.contributor.authorMorelli, Maria Cristina
dc.contributor.authorTamè, Mariarosa
dc.contributor.authorBusutti, Marco
dc.contributor.authorComai, Giorgia
dc.contributor.authorPotena, Luciano
dc.contributor.authorSalvaterra, Elena
dc.contributor.authorFeltrin, Giuseppe
dc.contributor.authorCillo, Umberto
dc.contributor.authorGerosa, Gino
dc.contributor.authorCananzi, Mara
dc.contributor.authorPiano, Salvatore
dc.contributor.authorBenetti, Elisa
dc.contributor.authorBurra, Patrizia
dc.contributor.authorLoy, Monica
dc.contributor.authorFurian, Lucrezia
dc.contributor.authorZaza, Gianluigi
dc.contributor.authorOnorati, Francesco
dc.contributor.authorCarraro, Amedeo
dc.contributor.authorGastaldon, Fiorella
dc.contributor.authorNordio, Maurizio
dc.contributor.authorKumar-Singh, Samir
dc.contributor.authorAbedini, Mahsa
dc.contributor.authorBoffetta, Paolo
dc.contributor.authorRodríguez-Baño, Jesús
dc.contributor.authorLazzarotto, Tiziana
dc.contributor.authorViale, Pierluigi
dc.contributor.authorTacconelli, Evelina
dc.contributor.authorOn Behalf Of The Orchestra Study Group Workpackage,
dc.date.accessioned2023-05-03T14:14:35Z
dc.date.available2023-05-03T14:14:35Z
dc.date.issued2022-05-12
dc.description.abstractPrevious studies assessing the antibody response (AbR) to mRNA COVID-19 vaccines in solid organ transplant (SOT) recipients are limited by short follow-up, hampering the analysis of AbR kinetics. We present the ORCHESTRA SOT recipients cohort assessed for AbR at first dose (t0), second dose (t1), and within 3 ± 1 month (t2) after the first dose. We analyzed 1062 SOT patients (kidney, 63.7%; liver, 17.4%; heart, 16.7%; and lung, 2.5%) and 5045 health care workers (HCWs). The AbR rates in the SOTs and HCWs were 52.3% and 99.4%. The antibody levels were significantly higher in the HCWs than in the SOTs (p
dc.identifier.doi10.3390/microorganisms10051021
dc.identifier.issn2076-2607
dc.identifier.pmcPMC9147204
dc.identifier.pmid35630462
dc.identifier.pubmedURLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9147204/pdf
dc.identifier.unpaywallURLhttps://www.mdpi.com/2076-2607/10/5/1021/pdf?version=1652496782
dc.identifier.urihttp://hdl.handle.net/10668/21436
dc.issue.number5
dc.journal.titleMicroorganisms
dc.journal.titleabbreviationMicroorganisms
dc.language.isoen
dc.organizationHospital Universitario Virgen del Rocío
dc.organizationInstituto de Biomedicina de Sevilla-IBIS
dc.pubmedtypeJournal Article
dc.rightsAttribution 4.0 International
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectCOVID-19
dc.subjectantibody response
dc.subjectmRNA vaccines
dc.subjectserology
dc.subjectsolid organ transplantation
dc.titleEvaluation of the Kinetics of Antibody Response to COVID-19 Vaccine in Solid Organ Transplant Recipients: The Prospective Multicenter ORCHESTRA Cohort.
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number10
dspace.entity.typePublication

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