Publication: Evaluation of the Kinetics of Antibody Response to COVID-19 Vaccine in Solid Organ Transplant Recipients: The Prospective Multicenter ORCHESTRA Cohort.
Loading...
Identifiers
Date
2022-05-12
Authors
Giannella, Maddalena
Righi, Elda
Pascale, Renato
Rinaldi, Matteo
Caroccia, Natascia
Gamberini, Chiara
Palacios-Baena, Zaira R
Caponcello, Giulia
Morelli, Maria Cristina
Tamè, Mariarosa
Advisors
Journal Title
Journal ISSN
Volume Title
Publisher
Metrics
Export
Abstract
Previous studies assessing the antibody response (AbR) to mRNA COVID-19 vaccines in solid organ transplant (SOT) recipients are limited by short follow-up, hampering the analysis of AbR kinetics. We present the ORCHESTRA SOT recipients cohort assessed for AbR at first dose (t0), second dose (t1), and within 3 ± 1 month (t2) after the first dose. We analyzed 1062 SOT patients (kidney, 63.7%; liver, 17.4%; heart, 16.7%; and lung, 2.5%) and 5045 health care workers (HCWs). The AbR rates in the SOTs and HCWs were 52.3% and 99.4%. The antibody levels were significantly higher in the HCWs than in the SOTs (p
Description
MeSH Terms
DeCS Terms
CIE Terms
Keywords
COVID-19, antibody response, mRNA vaccines, serology, solid organ transplantation