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The L162V polymorphism of the PPARA gene is associated with stage C of heart failure.

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dc.contributor.authorBeaumont, Javier
dc.contributor.authorArias, Teresa
dc.contributor.authorLópez, Begoña
dc.contributor.authorZalba, Guillermo
dc.contributor.authorBelloqui, Oscar
dc.contributor.authorGarcía-Bolao, Ignacio
dc.contributor.authorBarba, Joaquín
dc.contributor.authorTeresa, Eduardo de
dc.contributor.authorDíez, Javier
dc.contributor.authoraffiliation[Beaumont,J; Arias,T; López,B; Zalba,G] Cntr for Applied Med Rsch, Pamplona, Spain. [Belloqui,O; García-Bolao,I; Valencia,F] Univ Clinic of Navarra, Pamplona, Spain. [Teresa,E de] Hospital Universitario Virgen de la Victoria, Málaga, Spain. [Díez,J] Cntr for Applied Med Rsch-Univ Clinic of Navarra, Pamplona, Spain.es
dc.date.accessioned2013-06-06T08:27:04Z
dc.date.available2013-06-06T08:27:04Z
dc.date.issued2009
dc.descriptionAbstract 1921. Contents: Volume 120, Issue 18 Supplement; November 3, 2009 / Abstracts From Scientific Sessions 2009es
dc.description.abstractIn human heart failure (HF) peroxisome proliferator-activated receptor alpha (PPAR alpha) is downregulated and consequently, the expression of genes involved in fatty acid oxidation repressed. The L162V (rs1800206) is a functional polymorphism of the human PPAR alpha gene (PPARA). In the present study we have investigated whether this polymorphism is associated with the development of stage C of HF.es
dc.description.versionYeses
dc.identifier.citationBeaumont, Javier; Arias, Teresa; Lopez, Begona; Zalba, Guillermo; Beloqui, Oscar; Garcia-Bolao, Ignacio; et al. The L162V polymorphism of the PPARA gene is associated with stage C of heart failure. Circulation. 2009;120(18 Suppl 2):S571es
dc.identifier.essn1524-4539
dc.identifier.issn0009-7322
dc.identifier.urihttp://hdl.handle.net/10668/1107
dc.journal.titleCirculation
dc.language.isoen
dc.publisherAmerican Heart Associationes
dc.relation.publisherversionhttp://circ.ahajournals.org/cgi/content/meeting_abstract/120/18_MeetingAbstracts/S571-b?sid=7b981245-4e2e-435d-a5a3-589cad6e01aces
dc.rights.accessRightsopen access
dc.subjectAcil-CoA Deshidrogenasaes
dc.subjectCartilla de ADNes
dc.subjectInsuficiencia Cardíacaes
dc.subjectPPAR alfaes
dc.subjectHumanoses
dc.subjectPlásmidoses
dc.subjectPolimorfismo Genéticoes
dc.subjectARN Mensajeroes
dc.subject.meshMedical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Oxidoreductases::Oxidoreductases Acting on CH-CH Group Donors::Acyl-CoA Dehydrogenaseses
dc.subject.meshMedical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleotides::Polynucleotides::Oligonucleotides::Oligodeoxyribonucleotides::DNA Primerses
dc.subject.meshMedical Subject Headings::Diseases::Cardiovascular Diseases::Heart Diseases::Heart Failurees
dc.subject.meshMedical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::DNA-Binding Proteins::Receptors, Cytoplasmic and Nuclear::Peroxisome Proliferator-Activated Receptors::PPAR alphaes
dc.subject.meshMedical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humanses
dc.subject.meshMedical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Plasmidses
dc.subject.meshMedical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism, Genetices
dc.subject.meshMedical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::RNA::RNA, Messengeres
dc.subject.meshMedical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Agedes
dc.titleThe L162V polymorphism of the PPARA gene is associated with stage C of heart failure.es
dc.typeconference presentation
dc.type.hasVersionVoR
dspace.entity.typePublication

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