Publication:
Distribution of Non-Persistent Endocrine Disruptors in Two Different Regions of the Human Brain.

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dc.contributor.authorvan der Meer, Thomas P
dc.contributor.authorArtacho-Cordón, Francisco
dc.contributor.authorSwaab, Dick F
dc.contributor.authorStruik, Dicky
dc.contributor.authorMakris, Konstantinos C
dc.contributor.authorWolffenbuttel, Bruce H R
dc.contributor.authorFrederiksen, Hanne
dc.contributor.authorvan Vliet-Ostaptchouk, Jana V
dc.date.accessioned2023-01-25T09:52:04Z
dc.date.available2023-01-25T09:52:04Z
dc.date.issued2017-09-13
dc.description.abstractNon-persistent endocrine disrupting chemicals (npEDCs) can affect multiple organs and systems in the body. Whether npEDCs can accumulate in the human brain is largely unknown. The major aim of this pilot study was to examine the presence of environmental phenols and parabens in two distinct brain regions: the hypothalamus and white-matter tissue. In addition, a potential association between these npEDCs concentrations and obesity was investigated. Post-mortem brain material was obtained from 24 individuals, made up of 12 obese and 12 normal-weight subjects (defined as body mass index (BMI) > 30 and BMI 30 and BMI
dc.identifier.doi10.3390/ijerph14091059
dc.identifier.essn1660-4601
dc.identifier.pmcPMC5615596
dc.identifier.pmid28902174
dc.identifier.pubmedURLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615596/pdf
dc.identifier.unpaywallURLhttps://www.mdpi.com/1660-4601/14/9/1059/pdf?version=1505381259
dc.identifier.urihttp://hdl.handle.net/10668/11577
dc.issue.number9
dc.journal.titleInternational journal of environmental research and public health
dc.journal.titleabbreviationInt J Environ Res Public Health
dc.language.isoen
dc.organizationIBS
dc.pubmedtypeJournal Article
dc.rightsAttribution 4.0 International
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectbisphenol-A
dc.subjectbrain
dc.subjecthypothalamus
dc.subjectmethylparaben
dc.subjectobesity
dc.subjectparabens
dc.subjectphenols
dc.subject.meshAdult
dc.subject.meshBrain
dc.subject.meshChromatography, Liquid
dc.subject.meshEndocrine Disruptors
dc.subject.meshEnvironmental Exposure
dc.subject.meshEnvironmental Pollutants
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshObesity
dc.subject.meshPilot Projects
dc.subject.meshTandem Mass Spectrometry
dc.titleDistribution of Non-Persistent Endocrine Disruptors in Two Different Regions of the Human Brain.
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number14
dspace.entity.typePublication

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