Publication:
Gender Differences in Outcomes Following a Pain-Free, Home-Based Exercise Program for Claudication.

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Date

2018-09-15

Authors

Manfredini, Roberto
Lamberti, Nicola
Manfredini, Fabio
Straudi, Sofia
Fabbian, Fabio
Rodriguez Borrego, Maria Aurora
Basaglia, Nino
Carmona Torres, Juan Manuel
Lopez Soto, Pablo Jesus

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Mary Ann Liebert, Inc. Publishers
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Abstract

Background: Peripheral artery disease (PAD) is a common cardiovascular pathology that affects mobility. In previous research, supervised exercise, a recommended treatment for claudication, was less effective in women. This study retrospectively investigated whether functional outcomes exhibit sex differences following a pain-free, home-based exercise program for PAD patients. Materials and Methods: Patients with PAD and claudication enrolled to a structured home-based program from 2003 to 2016 were studied. The program was prescribed at the hospital and based on two daily 10-minute pain-free walking sessions at progressively increasing speed. Outcome measures, which were assessed at baseline and discharge, were pain threshold speed (PTS) and maximal (Smax) during a treadmill test and pain-free walking distance (PFWD) and total distance walked in 6 minutes (6MWD). The ankle-brachial index (ABI), program duration, and patient adherence were determined. Results: A total of 1007 patients (women; n = 264; 26%) were enrolled. At baseline, compared to men, women exhibited similar ABI values but lower PTS and PFWD values (p 

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MeSH Terms

Aged
Aged, 80 and over
Ankle Brachial Index
Cohort Studies
Exercise Therapy
Female
Humans
Intermittent Claudication
Italy
Male
Middle Aged
Patient Compliance
Peripheral Arterial Disease
Physical Functional Performance
Retrospective Studies
Sex Characteristics
Treatment Outcome

DeCS Terms

Índice tobillo braquial
Terapia por ejercicio
Rendimiento físico funcional
Enfermedad arterial periférica
Claudicación intermitente
Cooperación del paciente

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Keywords

exercise therapy, gender, peripheral artery disease, rehabilitation, women

Citation

Manfredini R, Lamberti N, Manfredini F, Straudi S, Fabbian F, Rodriguez Borrego MA, et al. Differences in Outcomes Following a Pain-Free, Home-Based Exercise Program for Claudication. J Womens Health (Larchmt). 2019 Sep;28(9):1313-1321.