Publication:
Urinary Tartaric Acid, a Biomarker of Wine Intake, Correlates with Lower Total and LDL Cholesterol.

dc.contributor.authorDomínguez-López, Inés
dc.contributor.authorParilli-Moser, Isabella
dc.contributor.authorArancibia-Riveros, Camila
dc.contributor.authorTresserra-Rimbau, Anna
dc.contributor.authorMartínez-González, Miguel Angel
dc.contributor.authorOrtega-Azorín, Carolina
dc.contributor.authorSalas-Salvadó, Jordi
dc.contributor.authorCastañer, Olga
dc.contributor.authorLapetra, José
dc.contributor.authorArós, Fernando
dc.contributor.authorFiol, Miquel
dc.contributor.authorSerra-Majem, Lluis
dc.contributor.authorPintó, Xavier
dc.contributor.authorGómez-Gracia, Enrique
dc.contributor.authorRos, Emilio
dc.contributor.authorLamuela-Raventós, Rosa M
dc.contributor.authorEstruch, Ramon
dc.date.accessioned2023-02-09T11:48:54Z
dc.date.available2023-02-09T11:48:54Z
dc.date.issued2021-08-22
dc.description.abstractPostmenopausal women are at higher risk of developing cardiovascular diseases due to changes in lipid profile and body fat, among others. The aim of this study was to evaluate the association of urinary tartaric acid, a biomarker of wine consumption, with anthropometric (weight, waist circumference, body mass index (BMI), and waist-to-height ratio), blood pressure, and biochemical variables (blood glucose and lipid profile) that may be affected during the menopausal transition. This sub-study of the PREDIMED (Prevención con Dieta Mediterránea) trial included a sample of 230 women aged 60-80 years with high cardiovascular risk at baseline. Urine samples were diluted and filtered, and tartaric acid was analyzed by liquid chromatography coupled to electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS). Correlations between tartaric acid and the study variables were adjusted for age, education level, smoking status, physical activity, BMI, cholesterol-lowering, antihypertensive, and insulin treatment, total energy intake, and consumption of fruits, vegetables, and raisins. A strong association was observed between wine consumption and urinary tartaric acid (0.01 μg/mg (95% confidence interval (CI): 0.01, 0.01), p-value
dc.identifier.doi10.3390/nu13082883
dc.identifier.essn2072-6643
dc.identifier.pmcPMC8399930
dc.identifier.pmid34445043
dc.identifier.pubmedURLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8399930/pdf
dc.identifier.unpaywallURLhttps://www.mdpi.com/2072-6643/13/8/2883/pdf?version=1629617232
dc.identifier.urihttp://hdl.handle.net/10668/18458
dc.issue.number8
dc.journal.titleNutrients
dc.journal.titleabbreviationNutrients
dc.language.isoen
dc.organizationSevilla
dc.pubmedtypeJournal Article
dc.pubmedtypeMulticenter Study
dc.rightsAttribution 4.0 International
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectMediterranean diet
dc.subjectPREDIMED
dc.subjectbiomarkers
dc.subjectbody fat
dc.subjectcardiovascular risk
dc.subjectlipid profile
dc.subjectmenopause
dc.subjectpolyphenols
dc.subjecttartaric acid
dc.subject.meshAged
dc.subject.meshAged, 80 and over
dc.subject.meshAlcohol Drinking
dc.subject.meshAnthropometry
dc.subject.meshBiomarkers
dc.subject.meshCardiovascular Diseases
dc.subject.meshCholesterol
dc.subject.meshCholesterol, LDL
dc.subject.meshCross-Sectional Studies
dc.subject.meshFemale
dc.subject.meshHeart Disease Risk Factors
dc.subject.meshHumans
dc.subject.meshMiddle Aged
dc.subject.meshRandomized Controlled Trials as Topic
dc.subject.meshTartrates
dc.subject.meshWine
dc.titleUrinary Tartaric Acid, a Biomarker of Wine Intake, Correlates with Lower Total and LDL Cholesterol.
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number13
dspace.entity.typePublication

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