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Serum angiopoietin-like 3 levels are elevated in obese non diabetic men but are unaffected during an oral glucose tolerance test.

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dc.contributor.authorGarces, Maria Fernanda
dc.contributor.authorBuell-Acosta, Julieth Daniela
dc.contributor.authorRodriguez-Navarro, Haiver Antonio
dc.contributor.authorPulido-Sanchez, Estefania
dc.contributor.authorRincon-Ramirez, Juan Jose
dc.contributor.authorMoreno-Ordoñez, Diana Carolina
dc.contributor.authorFranco-Vega, Roberto
dc.contributor.authorRoncancio-Muñoz, Jhoan Sebastian
dc.contributor.authorBurgos-Cardenas, Alvaro Javier
dc.contributor.authorLacunza, Ezequiel
dc.contributor.authorCastaño, Justo P.
dc.contributor.authorDieguez, Carlos
dc.contributor.authorNogueiras, Ruben
dc.contributor.authorSanchez, Elizabeth
dc.contributor.authorCaminos, Jorge Eduardo
dc.date.accessioned2023-02-09T10:38:01Z
dc.date.available2023-02-09T10:38:01Z
dc.date.issued2020-09-29
dc.description.abstractThis study aimed to determine ANGPTL3 serum levels in healthy young lean and obese non-diabetic men during an oral glucose tolerance test (OGTT) and correlate them with anthropometric, biochemical and hormonal parameters. A case-control study was carried out and 30 young obese non-diabetic (23.90 ± 3.84 years and BMI 37.92 ± 4.85 kg/m2) and 28 age-matched healthy lean (24.56 ± 3.50 years and BMI of 22.10 ± 1.72 kg/m2) men were included in this study. The primary outcome measures were serum basal ANGPTL3 and ANGPTL3-area under the curve (AUC) levels. The percentage of body fat was measured by dual-energy X-ray absorptiometry and biochemical, hormonal and insulin resistance indices were determined. Basal ANGPTL3 and ANGPTL3-AUC levels were significantly elevated (p 
dc.identifier.citationGarcés MF, Buell-Acosta JD, Rodríguez-Navarro HA, Pulido-Sánchez E, Rincon-Ramírez JJ, Moreno-Ordóñez DC, et al. Serum angiopoietin-like 3 levels are elevated in obese non diabetic men but are unaffected during an oral glucose tolerance test. Sci Rep. 2020 Dec 3;10(1):21118
dc.identifier.doi10.1038/s41598-020-77961-8
dc.identifier.essn2045-2322
dc.identifier.pmcPMC7713064
dc.identifier.pmid33273510
dc.identifier.pubmedURLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7713064/pdf
dc.identifier.unpaywallURLhttps://www.nature.com/articles/s41598-020-77961-8.pdf
dc.identifier.urihttp://hdl.handle.net/10668/16728
dc.issue.number1
dc.journal.titleScientific reports
dc.journal.titleabbreviationSci Rep
dc.language.isoen
dc.organizationHospital Universitario Reina Sofía
dc.organizationInstituto Maimónides de Investigación Biomédica de Córdoba-IMIBIC
dc.page.number9
dc.publisherNature Publishing Group
dc.pubmedtypeJournal Article
dc.pubmedtypeResearch Support, Non-U.S. Gov't
dc.rightsAttribution 4.0 International
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subject.decsDiabetes mellitus
dc.subject.decsGlucemia
dc.subject.decsProteina 3 similar a la angiopoyetina
dc.subject.decsPrueba de tolerancia a la glucosa
dc.subject.decsResistencia a la insulina
dc.subject.decsAyuno
dc.subject.decsInsulina
dc.subject.decsObesidad
dc.subject.meshAngiopoietin-Like Protein 3
dc.subject.meshAngiopoietin-like Proteins
dc.subject.meshBlood Glucose
dc.subject.meshDiabetes Mellitus
dc.subject.meshFasting
dc.subject.meshGlucose Tolerance Test
dc.subject.meshHumans
dc.subject.meshInsulin
dc.subject.meshInsulin Resistance
dc.subject.meshMale
dc.subject.meshObesity
dc.subject.meshYoung Adult
dc.titleSerum angiopoietin-like 3 levels are elevated in obese non diabetic men but are unaffected during an oral glucose tolerance test.
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number10
dspace.entity.typePublication

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