Publication: Serum angiopoietin-like 3 levels are elevated in obese non diabetic men but are unaffected during an oral glucose tolerance test.
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Identifiers
Date
2020-09-29
Authors
Garces, Maria Fernanda
Buell-Acosta, Julieth Daniela
Rodriguez-Navarro, Haiver Antonio
Pulido-Sanchez, Estefania
Rincon-Ramirez, Juan Jose
Moreno-Ordoñez, Diana Carolina
Franco-Vega, Roberto
Roncancio-Muñoz, Jhoan Sebastian
Burgos-Cardenas, Alvaro Javier
Lacunza, Ezequiel
Advisors
Journal Title
Journal ISSN
Volume Title
Publisher
Nature Publishing Group
Abstract
This study aimed to determine ANGPTL3 serum levels in healthy young lean and obese non-diabetic men during an oral glucose tolerance test (OGTT) and correlate them with anthropometric, biochemical and hormonal parameters. A case-control study was carried out and 30 young obese non-diabetic (23.90 ± 3.84 years and BMI 37.92 ± 4.85 kg/m2) and 28 age-matched healthy lean (24.56 ± 3.50 years and BMI of 22.10 ± 1.72 kg/m2) men were included in this study. The primary outcome measures were serum basal ANGPTL3 and ANGPTL3-area under the curve (AUC) levels. The percentage of body fat was measured by dual-energy X-ray absorptiometry and biochemical, hormonal and insulin resistance indices were determined. Basal ANGPTL3 and ANGPTL3-AUC levels were significantly elevated (p
Description
MeSH Terms
Angiopoietin-Like Protein 3
Angiopoietin-like Proteins
Blood Glucose
Diabetes Mellitus
Fasting
Glucose Tolerance Test
Humans
Insulin
Insulin Resistance
Male
Obesity
Young Adult
Angiopoietin-like Proteins
Blood Glucose
Diabetes Mellitus
Fasting
Glucose Tolerance Test
Humans
Insulin
Insulin Resistance
Male
Obesity
Young Adult
DeCS Terms
Diabetes mellitus
Glucemia
Proteina 3 similar a la angiopoyetina
Prueba de tolerancia a la glucosa
Resistencia a la insulina
Ayuno
Insulina
Obesidad
Glucemia
Proteina 3 similar a la angiopoyetina
Prueba de tolerancia a la glucosa
Resistencia a la insulina
Ayuno
Insulina
Obesidad
CIE Terms
Keywords
Citation
Garcés MF, Buell-Acosta JD, Rodríguez-Navarro HA, Pulido-Sánchez E, Rincon-Ramírez JJ, Moreno-Ordóñez DC, et al. Serum angiopoietin-like 3 levels are elevated in obese non diabetic men but are unaffected during an oral glucose tolerance test. Sci Rep. 2020 Dec 3;10(1):21118