Publication: Visualization of coronary arteries in paediatric patients using whole-heart coronary magnetic resonance angiography: comparison of image-navigation and the standard approach for respiratory motion compensation
Loading...
Identifiers
Date
2019-02-25
Authors
Velasco Forte, Mari Nieves
Valverde, Israel
Prabhu, Nanda
Correia, Teresa
Narayan, Srinivas Ananth
Bell, Aaron
Mathur, Sujeev
Razavi, Reza
Hussain, Tarique
Pushparajah, Kuberan
Advisors
Journal Title
Journal ISSN
Volume Title
Publisher
BioMed Central Ltd.
Metrics
Export
Abstract
Aims: To investigate the use of respiratory motion compensation using image-based navigation (iNAV) with constant respiratory efficiency using single end-expiratory thresholding (CRUISE) for coronary magnetic resonance angiography (CMRA), and compare it to the conventional diaphragmatic navigator (dNAV) in paediatric patients with congenital or suspected heart disease.
Methods: iNAV allowed direct tracking of the respiratory heart motion and was generated using balanced steady state free precession startup echoes. Respiratory gating was achieved using CRUISE with a fixed 50% efficiency. Whole-heart CMRA was acquired with 1.3 mm isotropic resolution. For comparison, CMRA with identical imaging parameters were acquired using dNAV. Scan time, visualization of coronary artery origins and mid-course, imaging quality and sharpness was compared between the two sequences.
Results: Forty patients (13 females; median weight: 44 kg; median age: 12.6, range: 3 months-17 years) were enrolled. 25 scans were performed in awake patients. A contrast agent was used in 22 patients. The scan time was significantly reduced using iNAV for awake patients (iNAV 7:48 ± 1:26 vs dNAV 9:48 ± 3:11, P = 0.01) but not for patients under general anaesthesia (iNAV = 6:55 ± 1:50 versus dNAV = 6:32 ± 2:16; P = 0.32). In 98% of the cases, iNAV image quality had an equal or higher score than dNAV. The visual score analysis showed a clear difference, favouring iNAV (P = 0.002). The right coronary artery and the left anterior descending vessel sharpness was significantly improved (iNAV: 56.8% ± 10.1% vs dNAV: 53.7% ± 9.9%, P < 0.002 and iNAV: 55.8% ± 8.6% vs dNAV: 53% ± 9.2%, P = 0.001, respectively).
Conclusion: iNAV allows for a higher success-rate and clearer depiction of the mid-course of coronary arteries in paediatric patients. Its acquisition time is shorter in awake patients and image quality score is equal or superior to the conventional method in most cases.ngenital or suspected heart disease.
Description
MeSH Terms
Medical Subject Headings::Persons::Persons::Age Groups::Adolescent
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Artifacts
Medical Subject Headings::Persons::Persons::Age Groups::Child
Medical Subject Headings::Persons::Persons::Age Groups::Child::Child, Preschool
Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Diagnostic Uses of Chemicals::Contrast Media
Medical Subject Headings::Anatomy::Cardiovascular System::Blood Vessels::Arteries::Coronary Vessels
Medical Subject Headings::Check Tags::Female
Medical Subject Headings::Diseases::Cardiovascular Diseases::Cardiovascular Abnormalities::Heart Defects, Congenital
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Persons::Persons::Age Groups::Infant
Medical Subject Headings::Check Tags::Male
Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Alcohols::Sugar Alcohols::Sorbitol::Meglumine
Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Organometallic Compounds
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Research Design::Sensitivity and Specificity::Predictive Value of Tests
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Evaluation Studies as Topic::Reproducibility of Results
Medical Subject Headings::Phenomena and Processes::Physical Phenomena::Time::Time Factors
Medical Subject Headings::Information Science::Information Science::Systems Analysis::Workflow
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Techniques, Cardiovascular::Angiography::Magnetic Resonance Angiography
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Magnetic Resonance Imaging::Magnetic Resonance Imaging, Cine
Medical Subject Headings::Phenomena and Processes::Circulatory and Respiratory Physiological Phenomena::Respiratory Physiological Phenomena::Respiratory Physiological Processes::Respiration
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Artifacts
Medical Subject Headings::Persons::Persons::Age Groups::Child
Medical Subject Headings::Persons::Persons::Age Groups::Child::Child, Preschool
Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Diagnostic Uses of Chemicals::Contrast Media
Medical Subject Headings::Anatomy::Cardiovascular System::Blood Vessels::Arteries::Coronary Vessels
Medical Subject Headings::Check Tags::Female
Medical Subject Headings::Diseases::Cardiovascular Diseases::Cardiovascular Abnormalities::Heart Defects, Congenital
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Persons::Persons::Age Groups::Infant
Medical Subject Headings::Check Tags::Male
Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Alcohols::Sugar Alcohols::Sorbitol::Meglumine
Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Organometallic Compounds
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Research Design::Sensitivity and Specificity::Predictive Value of Tests
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Evaluation Studies as Topic::Reproducibility of Results
Medical Subject Headings::Phenomena and Processes::Physical Phenomena::Time::Time Factors
Medical Subject Headings::Information Science::Information Science::Systems Analysis::Workflow
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Techniques, Cardiovascular::Angiography::Magnetic Resonance Angiography
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Magnetic Resonance Imaging::Magnetic Resonance Imaging, Cine
Medical Subject Headings::Phenomena and Processes::Circulatory and Respiratory Physiological Phenomena::Respiratory Physiological Phenomena::Respiratory Physiological Processes::Respiration
DeCS Terms
CIE Terms
Keywords
Coronary magnetic resonance angiography, Respiratory motion compensation, Coronary artery disease, Image-based navigation, Magnetic resonance angiography, Angiografía por resonancia magnética, Enfermedad de la arteria coronaria
Citation
Velasco Forte MN, Valverde I, Prabhu N, Correia T, Narayan SA, Bell A, et al. Visualization of coronary arteries in paediatric patients using whole-heart coronary magnetic resonance angiography: comparison of image-navigation and the standard approach for respiratory motion compensation. J Cardiovasc Magn Reson. 2019 Feb 25;21(1):13.