RT Journal Article
T1 Visualization of coronary arteries in paediatric patients using whole-heart coronary magnetic resonance angiography: comparison of image-navigation and the standard approach for respiratory motion compensation
A1 Velasco Forte, Mari Nieves
A1 Valverde, Israel
A1 Prabhu, Nanda
A1 Correia, Teresa
A1 Narayan, Srinivas Ananth
A1 Bell, Aaron
A1 Mathur, Sujeev
A1 Razavi, Reza
A1 Hussain, Tarique
A1 Pushparajah, Kuberan
A1 Henningsson, Markus
K1 Coronary magnetic resonance angiography
K1 Respiratory motion compensation
K1 Coronary artery disease
K1 Image-based navigation
K1 Magnetic resonance angiography
K1 Angiografía por resonancia magnética
K1 Enfermedad de la arteria coronaria
AB Aims: To investigate the use of respiratory motion compensation using image-based navigation (iNAV) with constant respiratory efficiency using single end-expiratory thresholding (CRUISE) for coronary magnetic resonance angiography (CMRA), and compare it to the conventional diaphragmatic navigator (dNAV) in paediatric patients with congenital or suspected heart disease.Methods: iNAV allowed direct tracking of the respiratory heart motion and was generated using balanced steady state free precession startup echoes. Respiratory gating was achieved using CRUISE with a fixed 50% efficiency. Whole-heart CMRA was acquired with 1.3 mm isotropic resolution. For comparison, CMRA with identical imaging parameters were acquired using dNAV. Scan time, visualization of coronary artery origins and mid-course, imaging quality and sharpness was compared between the two sequences.Results: Forty patients (13 females; median weight: 44 kg; median age: 12.6, range: 3 months-17 years) were enrolled. 25 scans were performed in awake patients. A contrast agent was used in 22 patients. The scan time was significantly reduced using iNAV for awake patients (iNAV 7:48 ± 1:26 vs dNAV 9:48 ± 3:11, P = 0.01) but not for patients under general anaesthesia (iNAV = 6:55 ± 1:50 versus dNAV = 6:32 ± 2:16; P = 0.32). In 98% of the cases, iNAV image quality had an equal or higher score than dNAV. The visual score analysis showed a clear difference, favouring iNAV (P = 0.002). The right coronary artery and the left anterior descending vessel sharpness was significantly improved (iNAV: 56.8% ± 10.1% vs dNAV: 53.7% ± 9.9%, P < 0.002 and iNAV: 55.8% ± 8.6% vs dNAV: 53% ± 9.2%, P = 0.001, respectively).Conclusion: iNAV allows for a higher success-rate and clearer depiction of the mid-course of coronary arteries in paediatric patients. Its acquisition time is shorter in awake patients and image quality score is equal or superior to the conventional method in most cases.ngenital or suspected heart disease.
PB BioMed Central Ltd.
SN 1097-6647
YR 2019
FD 2019-02-25
LK http://hdl.handle.net/10668/3175
UL http://hdl.handle.net/10668/3175
LA en
NO Velasco Forte MN, Valverde I, Prabhu N, Correia T, Narayan SA, Bell A, et al. Visualization of coronary arteries in paediatric patients using whole-heart coronary magnetic resonance angiography: comparison of image-navigation and the standard approach for respiratory motion compensation. J Cardiovasc Magn Reson. 2019 Feb 25;21(1):13.
DS RISalud
RD Apr 7, 2025