Montesinos, PBallesteros, JMartinez Cuadron, DMartinez Lopez, JSerrano, JPerez de Oteyza, JFernandez, PRodriguez Macias, GVidriales, BHerrera, PTormo, MBergua, JGarcia, RVives, SFernandez, MALavilla, EJimenez, SPerez Simon, JASimiele, AGonzalez, AGonzalez, BBurgaleta, CLopez, JABethancourt, CBautista, GAlonso, AColorado, MSierra, JNavas, BHernandez Rivas, JAVera, JAAmador, LCordoba, Rde la Fuente, ARamos, FCervero, CJRayon, CSalamero, OMarti, ELoez, AOlave, TGaspar, MGorrochategui, JRojas, JLGomez, CHernandez, PRobles, AOrtega, IVilloria, JMoscardo, FTroconiz, ISanz, MA2016-10-032016-10-032016-06Montesinos P, Ballesteros J, Martinez Cuadron D. Martinez Lopez J, Serrano J, Perez de Oteyza J et al. An ex vivo native environment precision medicine test shows high clinical correlation with responses to first line acute myeloid leukemia treatment. Haematologica. 2016; 101 (s1) P5690390-6078http://hdl.handle.net/10668/2442This novel test is able to predict the clinical response to Ida+Ara-C induction with overall correlation and predictive values of 80%, higher than ever achieved. Considering this result and current clinical response rate of 66.7% (70% in this study), clear clinical benefits can be achieved with the use of the test. Adding the cytogenetic risk profile further increase the correlation to 90%. Thus this novel test may be valuable information to guide 1st line patient therapyenAdultoMédula óseaCitarabinaAmbienteHumanosIdarrubicinaQuimioterapia de inducciónMantenimientoMedical Subject Headings::Named Groups::Persons::Age Groups::AdultMedical Subject Headings::Anatomy::Hemic and Immune Systems::Immune System::Bone MarrowMedical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleosides::Pyrimidine Nucleosides::CytidineMedical Subject Headings::Phenomena and Processes::Biological Phenomena::Ecological and Environmental Phenomena::EnvironmentMedical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::HumansMedical Subject Headings::Chemicals and Drugs::Organic Chemicals::Hydrocarbons::Hydrocarbons, Cyclic::Hydrocarbons, Aromatic::Polycyclic Hydrocarbons, Aromatic::Naphthacenes::Anthracyclines::Daunorubicin::IdarubicinMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Drug Therapy::Induction ChemotherapyMedical Subject Headings::Health Care::Health Care Facilities, Manpower, and Services::MaintenanceMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Remission InductionAn ex vivo native environment precision medicine test shows high clinical correlation with responses to first line acute myeloid leukemia treatmentconference presentationopen access1592-8721