Toledano-Osorio, ManuelToledano, ManuelManzano-Moreno, Francisco JavierVallecillo, CristinaVallecillo-Rivas, MartaRodriguez-Archilla, AlbertoOsorio, Raquel2022-09-162022-09-162021-04-06Toledano-Osorio M, Toledano M, Manzano-Moreno FJ, Vallecillo C, Vallecillo-Rivas M, Rodriguez-Archilla A, et al. Alveolar Bone Ridge Augmentation Using Polymeric Membranes: A Systematic Review and Meta-Analysis. Polymers. 2021 Apr 6;13(7):1172http://hdl.handle.net/10668/4050Alveolar bone ridge resorption occurred after natural teeth loss and it can restrict the possibility of dental implants placement. The use of bone regenerative procedures is frequently required. The existing evidence regarding the efficacy of horizontal bone ridge augmentation trough guided bone regeneration (GBR) using polymeric membranes was stated. A systematic review and meta-analysis were performed. Electronic and manual literature searches were conducted. Screening process was done using the National Library of Medicine (MEDLINE by PubMed), Embase, and the Cochrane Oral Health. Included articles were randomized controlled trials and observational studies. Weighted means were calculated. Heterogeneity was determined using Higgins (I2). If I2 > 50% a random-effects model was applied. It was found that the mean of horizontal bone gain was 3.95 mm, ranging from 3.19 to 4.70 mm (confidence interval 95%). Heterogeneity is I2 = 99% (confidence interval 95%) and significance of the random-effects model was p < 0.001. The complications rate was 8.4% and membrane exposure was the most frequent. Through this study, we were able to conclude that the existing scientific evidence suggests that GBR using polymeric membranes is a predictable technique for achieving horizontal bone augmentation, thus, permitting a proper further implant placement.enAtribución 4.0 Internacionalhttp://creativecommons.org/licenses/by/4.0/Bone regenerationPolymeric membraneBone substitutesRidge augmentationSystematic reviewRegeneración óseaSustitutos de huesosAumento de la cresta alveolarDental implantsImplantes dentalesRevisión sistemáticaMetaanálisisBases de Datos BibliográficasMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Dentistry::Prosthodontics::Dental Prosthesis::Dental ImplantsMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Confidence IntervalsMedical Subject Headings::Anthropology, Education, Sociology and Social Phenomena::Social Sciences::Government::Federal Government::United States Government Agencies::United States Dept. of Health and Human Services::National Institutes of Health (U.S.)::National Library of Medicine (U.S.)Medical Subject Headings::Health Care::Population Characteristics::Health::Oral HealthMedical Subject Headings::Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Musculoskeletal Physiological Phenomena::Musculoskeletal Physiological Processes::Bone Remodeling::Bone RegenerationMedical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Physics::ElectronicsMedical Subject Headings::Information Science::Information Science::Medical Informatics::Medical Informatics Applications::Information Systems::Databases as Topic::Databases, BibliographicMedical Subject Headings::Information Science::Information Science::Information Centers::Libraries::Libraries, Medicalreview article33917475Acceso abierto10.3390/polym130711722073-4360PMC8038790