Fernandez, Mariana FPumarega, JosePorta, MiquelMolina-Molina, Jose ManuelArrebola, Juan POlea, Nicolas2023-01-252023-01-252017-03-10http://hdl.handle.net/10668/10957We aimed to assess changes in the total effective xenoestrogen burden (TEXB) -a biomarker of combined effect of mixtures of xenoestrogens- in breast cancer patients at surgery (breast adipose tissue) and at different time points during an 18-month follow-up (abdominal adipose tissue), and to analyze the potential influence of socio-demographic, reproductive, tumor, and treatment characteristics on TEXB levels. TEXB-alpha (due to persistent organohalogenated chemicals) and TEXB-beta (due mainly to endogenous estrogens) were quantified in 44 women. TEXB values significantly increased over follow-up (penTEXBbreast cancercancer treatmentchemotherapyestrogen receptor tumorsfollow uptotal effective xenoestrogen burdenAdipose TissueAdultAgedAged, 80 and overBody BurdenBreast NeoplasmsEnvironmental PollutantsEstrogensFemaleHumansHydrocarbons, ChlorinatedMiddle AgedPostoperative Periodresearch article28288811open access10.1016/j.reprotox.2017.03.0071873-1708http://repositori.upf.edu/bitstream/10230/34032/1/fernandez-rto-chan.pdf