Trujillo, HernandoFernández-Ruiz, MarioGutiérrez, EduardoSevillano, ÁngelCaravaca-Fontán, FernandoMorales, EnriqueLópez-Medrano, FranciscoAguado, José MaríaPraga, ManuelAndrés, Amado2025-01-072025-01-072020-11-29https://hdl.handle.net/10668/25414Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) might increase the risk of invasive pulmonary aspergillosis (IPA). Although several case reports and small series have been reported in the general population, scarce information is available regarding coronavirus disease 2019 (COVID-19)-associated IPA in the setting of solid organ transplantation. We describe a case of a kidney transplant recipient with severe COVID-19 that was subsequently diagnosed with probable IPA on the basis of the repeated isolation of Aspergillus fumigatus in sputum cultures, repeatedly increased serum (1 → 3)-β-d-glucan levels, and enlarging cavitary nodules in the CT scan. The evolution was favorable after initiation of isavuconazole and nebulized liposomal amphotericin B combination therapy and the withdrawal of immunosuppression.encoronavirus disease 2019invasive pulmonary aspergillosiskidney transplantation.severe acute respiratory syndrome coronavirus 2solid organ transplantationAcute Kidney InjuryAdministration, InhalationAmphotericin BAnti-Bacterial AgentsAntibodies, Monoclonal, HumanizedAntifungal AgentsAzithromycinCOVID-19CeftriaxoneDeprescriptionsFemaleGlucocorticoidsGraft RejectionHumansHydroxychloroquineHyperoxaluria, PrimaryImmunoglobulins, IntravenousImmunologic FactorsImmunosuppressive AgentsInvasive Pulmonary AspergillosisKidney Failure, ChronicKidney TransplantationMiddle AgedMycophenolic AcidNitrilesOxygen Inhalation TherapyPrednisonePyridinesRenal DialysisSARS-CoV-2SputumTacrolimusTomography, X-Ray ComputedTriazolesresearch article33185971open access10.1111/tid.135011399-3062https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/tid.13501