Picchio, Camila ALens, SabelaHernandez-Guerra, ManuelArenas, JuanAndrade, Raúl JCrespo, JavierGarcía-Samaniego, JavierRomero-Gómez, ManuelTurnes, JuanCalleja, José LuisSimón, Miguel ÁngelWhite, Trenton MRiveiro-Barciela, MarPocurull, AnnaMorales-Arraez, DaliaGómez, AlexandraButi, MariaLazarus, Jeffrey V2025-01-072025-01-072021-12-17https://hdl.handle.net/10668/26952Chronic viral hepatitis infection affects an estimated 325 million people globally. People who initiate treatment after significant disease progression face increased risk of severe liver complications and death. Data are scarce on the characteristics and risk factors of people who present late to care in Spain and globally. Data were collected from January 2018 to December 2019 to report late presentation (LP) to specialist care at 11 large university hospitals in Spain to assess related risk factors using a multivariable logistic regression model. 2290 (CHB = 505, CHC = 1785) patients were analysed, with 581 (25.2%) presenting late. Hepatitis C patients more frequently reported LP compared to hepatitis B patients (28.1% vs 15.0%; p enAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/AdultAgedFemaleHepatitis B, ChronicHepatitis C, ChronicHospitals, TeachingHumansMaleMiddle AgedRegistriesRetrospective StudiesSpainresearch article34921156open access10.1038/s41598-021-01885-02045-2322PMC8683418https://www.nature.com/articles/s41598-021-01885-0.pdfhttps://pmc.ncbi.nlm.nih.gov/articles/PMC8683418/pdf