Valdivielso, PRamírez-Bollero, JPérez-López, C2015-01-272015-01-272014-10-15Valdivielso P., Ramírez-Bollero J., Pérez-López C. Peripheral arterial disease, type 2 diabetes and postprandial lipidaemia: Is there a link?. World Journal of Diabetes. 2014;5(5):577-5851948-9358http://hdl.handle.net/10668/1803Peripheral arterial disease, manifested as intermittent claudication or critical ischaemia, or identified by an ankle/brachial index < 0.9, is present in at least one in every four patients with type 2 diabetes mellitus. Several reasons exist for peripheral arterial disease in diabetes. In addition to hyperglycaemia, smoking and hypertension, the dyslipidaemia that accompanies type 2 diabetes and is characterised by increased triglyceride levels and reduced high-density lipoprotein cholesterol concentrations also seems to contribute to this association. Recent years have witnessed an increased interest in postprandial lipidaemia, as a result of various prospective studies showing that non-fasting triglycerides predict the onset of arteriosclerotic cardiovascular disease better than fasting measurements do. Additionally, the use of certain specific postprandial particle markers, such as apolipoprotein B-48, makes it easier and more simple to approach the postprandial phenomenon. Despite this, only a few studies have evaluated the role of postprandial triglycerides in the development of peripheral arterial disease and type 2 diabetes. The purpose of this review is to examine the epidemiology and risk factors of peripheral arterial disease in type 2 diabetes, focusing on the role of postprandial triglycerides and particles.enPeripheral arterial diseaseType 2 diabetesPostprandial lipidaemiaApolipoprotein B-48Anklebrachial indexNon-fasting triglyceridesHiperlipidemiasDiabetes mellitus tipo 2Enfermedad arterial periféricaHDL-ColesterolLDL-ColesterolApolipoproteína B-48Hemoglobina A GlucosiladaTriglicéridosÍndice tobillo braquialMedical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Lipid Metabolism Disorders::Dyslipidemias::HyperlipidemiasMedical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Diabetes Mellitus::Diabetes Mellitus, Type 2Medical Subject Headings::Chemicals and Drugs::Lipids::Lipoproteins::Lipoproteins, HDL::Cholesterol, HDLMedical Subject Headings::Chemicals and Drugs::Lipids::Lipoproteins::Lipoproteins, LDL::Cholesterol, LDLMedical Subject Headings::Chemicals and Drugs::Carbohydrates::Glycosides::Hemoglobin A, GlycosylatedMedical Subject Headings::Chemicals and Drugs::Lipids::Glycerides::TriglyceridesMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosisresearch articleopen access10.4239/wjd.v5.i5.5771948-9358