Carbajo, DanielRuiz-Sánchez, Antonio JesúsNájera, FranciscoPérez-Inestrosa, EzequielAlfonso, Ignacio2023-02-092023-02-092021http://hdl.handle.net/10668/16982The use of aminals in dynamic covalent chemistry is slightly underexplored, probably due to their inherent instability. Here we report the spontaneous [2+2] macrocyclization of tetrakis(aminals). Their unexpected stability and structural modularity, the dynamic nature of the connections and their water tolerance make them appealing systems for future applications as stimulus-responsive materials.enAttribution-NonCommercial 4.0 Internationalhttp://creativecommons.org/licenses/by-nc/4.0/research article33448267open access10.1039/d0cc07184f1364-548Xhttps://pubs.rsc.org/en/content/articlepdf/2021/cc/d0cc07184f