Muñoz, GerardBuxó, Mariade Gracia, JavierOlveira, CasildaMartinez-Garcia, Miguel AngelGiron, RosaPolverino, EvaAlvarez, AntonioBirring, Surinder SVendrell, Montserrat2023-01-252023-01-252016-02-22http://hdl.handle.net/10668/9856The Leicester Cough Questionnaire (LCQ) has been validated in non-cystic fibrosis bronchiectasis (NCFBC). The present study aimed to create and validate a Spanish version of the LCQ (LCQ-Sp) in NCFBC. The LCQ-Sp was developed following a standardized protocol. For reliability, we assessed internal consistency and the change in score over a 15-day period in stable state. For responsiveness, we assessed the change in scores between visit 1 and the first exacerbation. For validity, we evaluated convergent validity through correlation with the Saint George's Respiratory Questionnaire (SGRQ) and discriminant validity. Two hundred fifty-nine patients (118 mild bronchiectasis, 90 moderate bronchiectasis and 47 severe bronchiectasis) were included. Internal consistency was high for the total scoring and good for the different domains (Cronbach's α: 0.86-0.91). The test-retest reliability shows an intraclass correlation coefficient of 0.87 for the total score. The mean LCQ-Sp score at visit 1 decreased at the beginning of an exacerbation (15.13 ± 4.06 vs. 12.24 ± 4.64; penBronchiectasiscoughpatient-reported outcomequality of lifequestionnaireAdultAgedBronchiectasisCoughDisease ProgressionFemaleHumansLongitudinal StudiesMaleMiddle AgedPatient Reported Outcome MeasuresProspective StudiesReproducibility of ResultsSeverity of Illness IndexSurveys and QuestionnairesTranslationsresearch article26902541open access10.1177/14799723166320051479-9731PMC5734594https://journals.sagepub.com/doi/pdf/10.1177/1479972316632005https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734594/pdf