Porriño-Bustamante, María LibradaAneiros-Fernández, JoséRetámero, Juan AntonioSánchez-López, JosefaFernández-Pugnaire, MarIa Antonia2016-11-092016-11-092016-03Porriño-Bustamante ML, Aneiros-Fernández J, Retámero JA, Sánchez-López J, Fernández-Pugnaire MA. Cutaneous lymphoid hyperplasia following vaccine for pollen hyposensitization. Indian J Dermatol Venereol Leprol. 2016; 82(2):193-50378-6323http://hdl.handle.net/10668/2507LetterCutaneous lymphoid hyperplasia is also known as cutaneous lymphocytoma. Cutaneous lymphoid hyperplasia belongs to the spectrum of cutaneous pseudolymphomas which are lymphocytic infiltrates with clinical or histological features that mimic cutaneous lymphomas but follow a benign course. Most of these are predominantly composed of B cells. Cutaneous lymphoid hyperplasia is usually idiopathic but sometimes is associated with arthropod bites, scabies, infections (Borrelia burgdorferi is the most commonly identified agent in Europe), drugs, tattoo pigments and vaccine residues. It is more frequent in middle aged Caucasian women (sex ratio F:M 3:1). Adverse effects of vaccination are usually benign and transient, generally consisting of mild erythema or pain at the site of injection. Less commonly, chronic papules or subcutaneous nodules may appear which have been related to aluminum-adsorbed vaccines. Some rare cases of cutaneous lymphoid hyperplasia secondary to hyposensitization vaccines have been reported.enArtrópodosLinfocitos BBorrelia burgdorferiSeudolinfomaVacunasMedical Subject Headings::Organisms::Eukaryota::Animals::Invertebrates::ArthropodsMedical Subject Headings::Anatomy::Cells::Antibody-Producing Cells::B-LymphocytesMedical Subject Headings::Organisms::Bacteria::Gram-Negative Bacteria::Gram-Negative Anaerobic Bacteria::Gram-Negative Anaerobic Straight, Curved, and Helical Rods::Spirochaetaceae::Borrelia::Borrelia burgdorferi Group::Borrelia burgdorferiMedical Subject Headings::Diseases::Hemic and Lymphatic Diseases::Lymphatic Diseases::PseudolymphomaMedical Subject Headings::Chemicals and Drugs::Complex Mixtures::Biological Agents::Vaccinesletter26765127open access10.4103/0378-6323.1735870973-3922