Guerendiain, MarcelaMayneris-Perxachs, JordiMontes, RosaLópez-Belmonte, GemmaMartín-Matillas, MiguelCastellote, Ana IMartín-Bautista, ElenaMartí, AmeliaMartínez, J AlfredoMoreno, LuisGaragorri, Jesús MªWärnberg, JuliaCaballero, JavierMarcos, AscensiónLópez-Sabater, M CarmenCampoy, CristinaEVASYON Study Group2023-01-252023-01-252015-11-07http://hdl.handle.net/10668/9642In vivo and in vitro evidence suggests that antioxidant vitamins and carotenoids may be key factors in the treatment and prevention of obesity and obesity-associated disorders. Hence, the objective of the present study was to determine the relationship between plasma lipid-soluble antioxidant vitamin and carotenoid levels and adiposity and cardio-metabolic risk markers in overweight and obese adolescents participating in a multidisciplinary weight loss programme. A therapeutic programme was conducted with 103 adolescents aged 12-17 years old and diagnosed with overweight or obesity. Plasma concentrations of α-tocopherol, retinol, β-carotene and lycopene, anthropometric indicators of general and central adiposity, blood pressure and biochemical parameters were analysed at baseline and at 2 and 6 months of treatment. Lipid-corrected retinol (P  Plasma lipid-soluble antioxidant vitamin and carotenoid levels are associated with reduced adiposity, greater weight loss and an improved cardio-metabolic profile in overweight and obese adolescents.enAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/Cardio-metabolic profileObese adolescentsPlasma antioxidant vitaminsPlasma carotenoidsWeight lossAdiposityAdolescentAnthropometryAntioxidantsApolipoproteinsCardiovascular DiseasesCarotenoidsChildCholesterolCohort StudiesDietFemaleFollow-Up StudiesHumansLycopeneMaleMetabolic SyndromeNutrition AssessmentOverweightPediatric ObesityRisk FactorsTriglyceridesVitamin AVitaminsalpha-Tocopherolbeta Caroteneresearch article26614254open access10.1016/j.clnu.2015.11.0011532-1983https://zaguan.unizar.es/record/75582/files/texto_completo.pdf