Plaza, VGiner, JCurto, EAlonso-Ortiz, M BOrue, M IVega, J MCosio, B G2023-02-082023-02-082019-10-08Plaza V, Giner J, Curto E, Alonso-Ortiz MB, Orue MI, Vega JM, Cosío BG; et al. Assessing Adherence by Combining the Test of Adherence to Inhalers With Pharmacy Refill Records. J Investig Allergol Clin Immunol. 2021 Feb 17;31(1):58-641018-9068http://hdl.handle.net/10668/15166The Global Initiative for Asthma (GINA) recommends the concurrent use of self-report and pharmacy refill data to assess treatment adherence. However, clinical evidence to support this combined approach is limited. Objective: To determine nonadherence to inhaler medication based on a validated questionnaire (Test of Adherence to Inhalers; TAI) and prescription refill data in a community sample of patients with chronic obstructive pulmonary disease (COPD) or asthma. Secondarily, we sought to determine the degree of concordance between these two measures. Cross-sectional, observational multicenter study in patients with asthma or COPD. Sociodemographic and clinical data were obtained from clinical records. Refill data were retrieved from electronic pharmacy databases. Participants completed the 12-item TAI during a single visit as part of routine care. Nonadherence was defined as TAI A total of 816 patients (mean age, 60) were included. Nonadherence rates were 58.1% (TAI) and 28.6% (PRR) compared with 64.6% for the combined data (P These findings confirm the GINA recommendations, indicating that concomitant use of the TAI and pharmacy refill data identifies a higher percentage of nonadherent asthma or COPD patients than either instrument alone.enAdherence to therapyAsthmaCOPDNebulizerPatient complianceSelf-reported successAsthmaCross-Sectional StudiesFemaleHumansMaleMedication AdherenceMiddle AgedNebulizers and VaporizersPrescriptionsPulmonary Disease, Chronic ObstructiveSelf ReportSpainSurveys and Questionnairesresearch article31599726Restricted AccessEnfermedad pulmonar obstructiva crónicaAsmaFarmaciaNebulizadores y vaporizadoresCaracterísticas de la residencia10.18176/jiaci.0461http://www.jiaci.org/revistas/doi10.18176_jiaci.0461_material-suppl_1.pdf