Auffret, VincentWebb, John GEltchaninoff, HélèneMuñoz-García, Antonio JHimbert, DominiqueTamburino, CorradoNombela-Franco, LuisNietlispach, FabianMorís, CésarRuel, MarcDager, Antonio ESerra, VicençCheema, Asim NAmat-Santos, Ignacio Jde Brito, Fábio SandoliLemos, Pedro AlvesAbizaid, AlexandreSarmento-Leite, RogérioDumont, EricBarbanti, MarcoDurand, EricAlonso Briales, Juan HVahanian, AlecBouleti, ClaireImmè, SebastianoMaisano, FrancescoDel Valle, RaquelBenitez, Luis MiguelGarcía Del Blanco, BrunoPuri, RishiPhilippon, FrançoisUrena, MarinaRodés-Cabau, Josep2023-01-252023-01-252017-07-19http://hdl.handle.net/10668/11432This study sought to assess the influence of baseline right bundle branch block (RBBB) on all-cause and cardiovascular mortality as well as sudden cardiac death (SCD) among patients undergoing transcatheter aortic valve replacement (TAVR). Few data exist regarding the late clinical impact of pre-existing RBBB in TAVR recipients. A total of 3,527 patients (mean age 82 ± 8 years, 50.1% men) were evaluated according to the presence of RBBB on baseline electrocardiography. Intraventricular conduction abnormalities were classified according to the American Heart Association, American College of Cardiology Foundation, and Heart Rhythm Society recommendations for standardization and interpretation of the electrocardiogram. TAVR complications and causes of death were defined according to Valve Academic Research Consortium 2 definitions. RBBB was present on baseline electrocardiography in 362 patients (10.3%) and associated with higher 30-day rates of permanent pacemaker implantation (PPI) (40.1% vs. 13.5%; p  Pre-existing RBBB was found in 10% of TAVR recipients and was associated with poorer clinical outcomes. Patients with baseline RBBB without permanent pacemakers at hospital discharge may be at especially high risk for high-degree atrioventricular block and/or SCD during follow-up. Future studies should evaluate strategies aimed at the early detection of patients at risk for late development of high-degree atrioventricular block.enoutcomespermanent pacemaker implantationright bundle branch blocksudden cardiac deathtranscatheter aortic valve replacementAgedAged, 80 and overAortic ValveAortic Valve StenosisBrazilBundle-Branch BlockCanadaCause of DeathDeath, Sudden, CardiacEchocardiographyElectrocardiographyEuropeFemaleHumansKaplan-Meier EstimateMaleMultivariate AnalysisProportional Hazards ModelsRisk FactorsTime FactorsTranscatheter Aortic Valve ReplacementTreatment Outcomeresearch article28734885open access10.1016/j.jcin.2017.05.0301876-7605https://doi.org/10.1016/j.jcin.2017.05.030