Redondo-Cerezo, EduardoSánchez-Capilla, Antonio DamiánTorre-Rubio, Paloma De LaTeresa, Javier De2015-08-132015-08-132014-11-14Redondo-Cerezo E, Sánchez-Capilla AD, Torre-Rubio P De La, Teresa J De. Wireless capsule endoscopy: perspectives beyond gastrointestinal bleeding. World J Gastroenterol. 2014. 20(42):15664-731007-9327http://hdl.handle.net/10668/1968Journal Article;Wireless capsule endoscopy (CE) is a technology developed for the endoscopic exploration of the small bowel. The first capsule model was approved by the Food and Drug Administration in 2001, and its first and essential indication was occult gastrointestinal (GI) bleeding. Over subsequent years, this technology has been refined to provide superior resolution, increased battery life, and capabilities to view different parts of the GI tract. Indeed, cases for which CE proved useful have increased significantly over the last few years, with new indications for the small bowel and technical improvements that have expanded its use to other parts of the GI tract, including the esophagus and colon. The main challenges in the development of CE are new devices with the ability to provide therapy, air inflation for a better vision of the small bowel, biopsy sampling systems attached to the capsule and the possibility to guide and move the capsule with an external motion control. In this article we review the current and new indications of CE, and the evolving technological changes shaping this technology, which has a promising potential in the coming future of gastroenterology.enWireless capsule endoscopyObscure gastrointestinal bleedingSmall bowel tumorsColon capsule endoscopyEsophageal capsule endoscopyEndoscopios en CápsulasEnfermedades GastrointestinalesNeoplasias IntestinalesIntestino DelgadoHemorragia GastrointestinalMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Equipment and Supplies::Diagnostic Equipment::Endoscopes::Endoscopes, Gastrointestinal::Capsule EndoscopesMedical Subject Headings::Diseases::Digestive System Diseases::Gastrointestinal DiseasesMedical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Gastrointestinal Neoplasms::Intestinal NeoplasmsMedical Subject Headings::Anatomy::Digestive System::Gastrointestinal Tract::Intestines::Intestine, SmallMedical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Hemorrhage::Gastrointestinal Hemorrhageresearch article25400450open access10.3748/wjg.v20.i42.156642219-2840PMC4229531