Rodriguez-Gonzalez, MoisesPérez-Reviriego, Alvaro A.Gómez-Guzmán, ElenaTejero-Hernández, María ÁngelesZorilla Sanz, AliciaValverde, Israel2022-12-162022-12-162021-04-10Rodriguez-Gonzalez M, Pérez-Reviriego AA, Gómez-Guzmán E, Tejero-Hernández MÁ, Sanz AZ, Valverde I. Primary cardiac fibroma in infants: A case report and review of cases of cardiac fibroma managed through orthotopic heart transplant. Ann Pediatr Cardiol. 2021 Apr-Jun;14(2):224-2270974-2069http://hdl.handle.net/10668/4522Cardiac fibromas (CF) are the second most common cardiac tumors in children. They can be aggressive tumors despite their benign histopathologic nature, accounting for the highest mortality rate among primary cardiac tumors. CF usually show a progressive growth and spontaneous regression is rare. Therefore, a complete surgical excision is the preferred therapeutic approach when patients become symptomatic or if mass-related life-threatening complications are anticipated, even in asymptomatic patients. However, some cases are not good candidates for surgical excision due to the impossibility of preserving a normal cardiac anatomy or function after the tumor resection. Orthotopic heart transplantation (OHT) can be an exceptional but adequate alternative for some giant unresectable CF in children. In this article, we report our experience with the case of a 7-month-old infant with a giant unresectable cardiac fibroma who was successfully managed through OHT.enAtribución-NoComercial-CompartirIgual 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-sa/4.0/Cardiac fibromaOrthotopic heart transplantInfantsMortalityPrimary cardiac tumorTrasplantesTrasplante de corazónNeoplasias cardíacasProcedimientos quirúrgicos cardíacosLactanteNiñoMortalidadMedical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::HumansMedical Subject Headings::Persons::Persons::Age Groups::ChildMedical Subject Headings::Persons::Persons::Age Groups::InfantMedical Subject Headings::Diseases::Neoplasms::Neoplasms by Histologic Type::Neoplasms, Connective and Soft Tissue::Neoplasms, Connective Tissue::Neoplasms, Fibrous Tissue::FibromaMedical Subject Headings::Diseases::Cardiovascular Diseases::Heart Diseases::Heart NeoplasmsMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Cardiovascular Surgical Procedures::Cardiac Surgical Procedures::Heart TransplantationMedical Subject Headings::Anatomy::Cardiovascular System::HeartMedical Subject Headings::Disciplines and Occupations::Health Occupations::Medicine::Specialties, Surgical::Thoracic Surgeryresearch article34103866open access10.4103/apc.APC_78_200974-5149PMC8174620