Notario-Barandiaran, LeyreNavarrete-Muñoz, Eva-MaríaValera-Gran, DesiréeHernández-Álvarez, ElenaDonoso-Navarro, EncarnaciónGonzález-Palacios, SandraGarcía-de-la-Hera, ManuelaFernández, Mariana F.Freire, CarmenVioque, Jesús2022-12-092022-12-092021-05-08Notario-Barandiaran L, Navarrete-Muñoz EM, Valera-Gran D, Hernández-Álvarez E, Donoso-Navarro E, González-Palacios S, et al. Biochemical Validation of a Self-Administered Food Frequency Questionnaire to Assess Diet Using Carotenoids and Vitamins E and D in Male Adolescents in Spain. Antioxidants. 2021 May 8;10(5):750http://hdl.handle.net/10668/4476Reliable tools to evaluate diet are needed, particularly in life periods such as adolescence in which a rapid rate of growth and development occurs. We assessed the biochemical validity of a self-administered food frequency questionnaire (FFQ) in a sample of Spanish male adolescents using carotenoids and vitamin E and D data. We analyzed data from 122 male adolescents aged 15-17 years of the INMA-Granada birth cohort study. Adolescents answered a 104-item FFQ and provided a non-fasting blood sample. Mean daily nutrient intakes and serum concentration were estimated for main carotenoids (lutein-zeaxanthin, β-cryptoxanthin, lycopene, α-carotene and β-carotene), vitamins E and D and also for fruit and vegetable intake. Pearson correlation coefficients (r) and the percentage of agreement (same or adjacent quintiles) between serum vitamin concentrations and energy-adjusted intakes were estimated. Statistically significant correlation coefficients were observed for the total carotenoids (r = 0.40) and specific carotenoids, with the highest correlation observed for lutein-zeaxanthin (r = 0.42) and the lowest for β-carotene (0.23). The correlation coefficient between fruit and vegetable intake and serum carotenoids was 0.29 (higher for vegetable intake, r = 0.33 than for fruit intake, r = 0.19). Low correlations were observed for vitamin E and D. The average percentage of agreement for carotenoids was 55.8%, and lower for vitamin E and D (50% and 41%, respectively). The FFQ may be an acceptable tool for dietary assessment among male adolescents in Spain.enAtribución 4.0 Internacionalhttp://creativecommons.org/licenses/by/4.0/Carotenoid intakeVitamin EVitamin DFruit and vegetable intakeFood frequency questionnaireAdolescenceBiochemical validityNutritional biomarkerDietCarotenoidesVitamina EVitamina DFrutasVerdurasIngestión de alimentosConducta alimentariaNutrición del adolescenteDietaMedical Subject Headings::Check Tags::MaleMedical Subject Headings::Persons::Persons::Age Groups::AdolescentMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort StudiesMedical Subject Headings::Technology and Food and Beverages::Food and Beverages::Food::FruitMedical Subject Headings::Chemicals and Drugs::Biological Factors::Pigments, Biological::Carotenoids::Xanthophylls::LuteinMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Nutrition AssessmentMedical Subject Headings::Geographical Locations::Geographic Locations::Europe::SpainMedical Subject Headings::Technology and Food and Beverages::Food and Beverages::Food::VegetablesMedical Subject Headings::Phenomena and Processes::Physiological Phenomena::Physiological Processes::Growth and DevelopmentMedical Subject Headings::Phenomena and Processes::Digestive System and Oral Physiological Phenomena::Digestive System Physiological Phenomena::Digestive System Processes::EatingMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::QuestionnairesMedical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 2-Ring::Benzopyrans::Vitamin EMedical Subject Headings::Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::DietMedical Subject Headings::Chemicals and Drugs::Polycyclic Compounds::Steroids::Secosteroids::Vitamin DMedical Subject Headings::Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Nutritional Requirements::Recommended Dietary AllowancesBiochemical Validation of a Self-Administered Food Frequency Questionnaire to Assess Diet Using Carotenoids and Vitamins E and D in Male Adolescents in Spainresearch article34066826Acceso abierto10.3390/antiox100507502076-3921PMC8151424