Sánchez-Torralvo, Francisco JoséPorras, NuriaRuiz-García, IgnacioMaldonado-Araque, CristinaGarcía-Olivares, MaríaGirón, María VictoriaGonzalo-Marín, MontserratOlveira, CasildaOlveira, Gabriel2023-05-032023-05-032022-08-17http://hdl.handle.net/10668/21495Background: Muscle ultrasonography of the quadriceps rectus femoris (QRF) is a technique on the rise in the assessment of muscle mass in application of nutritional assessment. The aim of the present study is to assess the usefulness of muscle ultrasonography in patients with cystic fibrosis, comparing the results with other body composition techniques such as anthropometry, bioelectrical impedance analysis (BIA), dual-energy X-ray absorptiometry (DXA), and handgrip strength (HGS). At the same time, we intend to assess the possible association with the nutritional and respiratory status. Methods: This was a prospective observational study in adult patients with cystic fibrosis in a clinically stable situation. Muscle ultrasonography of the QRF was performed, and the results were compared with other measures of body composition: anthropometry, BIA, and DXA. HGS was used to assess muscle function. Respiratory parameters were collected, and nutritional status was assessed using Global Leadership Initiative on Malnutrition (GLIM) criteria. Results: A total of 48 patients were included, with a mean age of 34.1 ± 8.8 years. In total, 24 patients were men, and 24 patients were women. Mean BMI was 22.5 ± 3.8 kg/m2. Mean muscular area rectus anterior (MARA) was 4.09 ± 1.5 cm2, and mean muscular circumference rectus was 8.86 ± 1.61 cm. A positive correlation was observed between the MARA and fat-free mass index (FFMI) determined by anthropometry (r = 0.747; penAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/GLIM criteriacystic fibrosismalnutritionmuscle massmuscle ultrasoundultrasonographyAbsorptiometry, PhotonAdultBody CompositionBody Mass IndexCystic FibrosisElectric ImpedanceFemaleHand StrengthHumansMaleMalnutritionNutrition AssessmentNutritional StatusQuadriceps MuscleUltrasonographyresearch article36014883open access10.3390/nu141633772072-6643PMC9415857https://www.mdpi.com/2072-6643/14/16/3377/pdf?version=1660830147https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415857/pdf