Merino Gallego, EstherGallardo Sánchez, FranciscoGallego Rojo, Francisco Javier2023-01-252023-01-2520181130-0108http://hdl.handle.net/10668/12888Tuberculosis (TB) is the most prevalent infection worldwide and affects one third of the population, predominantly in developing countries. Intestinal TB (ITB) is the sixth most frequent extra-pulmonary TB infection. Crohn's disease (CD) is a chronic inflammatory bowel disease that arises from the interaction of immunological, environmental and genetic factors. Due to changes in the epidemiology of both diseases, distinguishing CD from ITB is a challenge, particularly in immunocompromised patients and those from areas where TB is endemic. Furthermore, both TB and CD have a predilection for the ileocecal area. In addition, they share very similar clinical, radiological and endoscopic findings. An incorrect diagnosis and treatment may increase morbidity and mortality. Thus, a great degree of caution is required as well as a familiarity with certain characteristics of the diseases, which will aid the differentiation between the two diseases.enCrohn DiseaseDiagnosis, DifferentialHumansTuberculosis, Gastrointestinalresearch article30168341open access10.17235/reed.2018.5184/2017https://doi.org/10.17235/reed.2018.5184/2017