Martinez-Garcia, Miguel AngelCampos-Rodriguez, FranciscoAlmendros, IsaacGarcia-Rio, FranciscoSanchez-de-la-Torre, ManuelFarre, RamonGozal, David2023-01-252023-01-252019-12-01Martinez-Garcia MA, Campos-Rodriguez F, Almendros I, Garcia-Rio F, Sanchez-de-la-Torre M, Farre R, et al. Cancer and Sleep Apnea: Cutaneous Melanoma as a Case Study. Am J Respir Crit Care Med. 2019 Dec 1;200(11):1345-1353.http://hdl.handle.net/10668/14299Melanoma is the most aggressive of all skin cancers and carries a very high mortality rate. Malignant transformation of melanocytes underlies the occurrence of this malignancy , which accounts for approximately 5% of all cutaneous malignancies , but it represents a very large proportion of cutaneous cancer –associated deaths. The incidence of cutaneous melanoma has been on the rise and is currently the 12th most prevalent cancer worldwide, carrying an age-standardized incidence rate of 3.0 per 100,000, reflecting well-established dynamic interdependencies between environmental factors and genetic susceptibility . Known risk factors for cutaneous melanoma include increased lifetime ultraviolet light exposure, family antecedents of melanoma , degree of skin pigmentation , and hair color . The identification of new risk factors for development of melanoma or factors related to melanoma aggressiveness is crucial to the development of new treatment options (1).enMelanomaIncidenceUltraviolet RaysHair ColorMelanocytesRisk FactorsAnimalsHumansMelanomaNeoplasmsSkin NeoplasmsSleep Apnea, Obstructiveresearch article31339332Restricted AccessMelanomaNeoplasiasFactores de riesgoIncidenciaElevaciónMelanocitosPigmentación de la pielColor del cabelloRayos ultravioletaNeoplasias cutáneas10.1164/rccm.201903-0577PP1535-4970PMC6884053https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884053https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884053/pdf