Arias-Santiago, SalvadorGutierrez-Salmeron, Maria TeresaBuendia-Eisman, AgustinGiron-Prieto, Maria SierraNaranjo-Sintes, Ramon2011-12-212011-12-212010-09Arias-Santiago S, Sanchez-Cano D, Callejas-Rubio JL, Fernández-Pugnaire MA, Ortego-Centeno N. Adalimumab treatment for SAPHO syndrome. Acta Derm Venereol. 2010 May;90(3):301–2.1651-2057http://hdl.handle.net/10668/261Varios estudios han analizado la relación entre la alopecia androgenética y las enfermedades cardiovasculares (especialmente las cardiopatías). Sin embargo pocos estudios han analizado los valores de lípidos en hombres y mujeres por separado. Este caso-control de estudio incluyó a 300 pacientes consecutivos ingresados ​​en una clínica para pacientes ambulatorios, 150 con la aparición temprana alopecia androgenética (80 hombres y mujeres 70) y 150 controles (80 hombres y mujeres 70) con enfermedades de la piel. Mujeres con alopecia androgénica mostraron significativamente más altos valores de triglicéridos (123,8 vs 89,43 mg / dl, p = 0,006), valores de colesterol total (196,1 vs 182,3 mg / dl, p = 0,014), los valores de LDL-C (114,1 vs 98,8 mg / dl , p = 0,0006) y más baja los valores de HDL-C (56,8 vs 67,7 mg / dl, p <0,0001) en comparación con los controles, respectivamente. Los hombres con alopecia androgénica mostraron significativamente más altos valores de triglicéridos (159,7 vs 128,7 mg / dl, p = 0,04) el colesterol total valores (198,3 vs 181,4 mg / dl, p = 0,006) y LDL-C los valores (124,3 vs 106,2, p = 0,0013) en comparación con alopecia hombres . Una mayor prevalencia de la dislipidemia en las mujeres y los hombres con alopecia androgénica se ha encontrado. Los valores elevados de lípidos en estos pacientes puede contribuir, junto con otros mecanismos, para el desarrollo de enfermedad cardiovascular en pacientes con alopecia androgénicaSeveral studies have analyzed the relationship between androgenetic alopecia and cardiovascular disease (mainly heart disease). However few studies have analyzed lipid values in men and women separately. This case-control study included 300 patients consecutively admitted to an outpatient clinic, 150 with early onset androgenetic alopecia (80 males and 70 females) and 150 controls (80 males and 70 females) with other skin diseases. Female patients with androgenic alopecia showed significant higher triglycerides values (123.8 vs 89.43 mg/dl, p = 0.006), total cholesterol values (196.1 vs 182.3 mg/dl, p = 0.014), LDL-C values (114.1 vs 98.8 mg/dl, p = 0.0006) and lower HDL-C values (56.8 vs 67.7 mg/dl, p <0.0001) versus controls respectively. Men with androgenic alopecia showed significant higher triglycerides values (159.7 vs 128.7 mg/dl, p = 0.04) total cholesterol values (198.3 vs 181.4 mg/dl, p = 0.006) and LDL-C values (124.3 vs 106.2, p = 0.0013) versus non-alopecic men. A higher prevalence of dyslipidemia in women and men with androgenic alopecia has been found. The elevated lipid values in these patients may contribute, alongside other mechanisms, to the development of cardiovascular disease in patient with androgenic alopecia.enEdad de InicioAlopeciaEstudios de Casos y ControlesDistribución de Chi-CuadradoColesterol LDLDislipidemiasMedición de RiesgoFactores de RiesgoMarcadores BiológicosÍndice de Masa CorporalColesterol HDLColesterolOportunidad RelativaColesterol, LDLDistribución por SexoPrevalenciaHumanosFemeninoMasculinoEspañaMedical Subject Headings::Diseases::Skin and Connective Tissue Diseases::Skin Diseases::Hair Diseases::Hypotrichosis::AlopeciaMedical Subject Headings::Chemicals and Drugs::Biological Factors::Biological MarkersMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Anthropometry::Body Weights and Measures::Body Mass IndexMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Case-Control StudiesMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Statistical Distributions::Chi-Square DistributionMedical Subject Headings::Chemicals and Drugs::Lipids::Sterols::CholesterolMedical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Lipoproteins::Lipoproteins, HDL::Cholesterol, HDLMedical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Lipoproteins::Lipoproteins, LDL::Cholesterol, LDLMedical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Lipid Metabolism Disorders::DyslipidemiasMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Odds RatioMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Vital Statistics::Morbidity::PrevalenceMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk AssessmentMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk FactorsMedical Subject Headings::Anthropology, Education, Sociology and Social Phenomena::Social Sciences::Demography::Sex DistributionMedical Subject Headings::Chemicals and Drugs::Lipids::Glycerides::TriglyceridesMedical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::HumansMedical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle AgedMedical Subject Headings::Named Groups::Persons::Age Groups::AdultMedical Subject Headings::Anatomy::Urogenital System::Genitalia::Genitalia, FemaleMedical Subject Headings::Anatomy::Urogenital System::Genitalia::Genitalia, MaleMedical Subject Headings::Geographicals::Geographic Locations::Europe::Spainresearch article20814623open access10.2340/00015555-09260001-5555