Gomez-España, M AGallego, JGonzalez-Flores, EMaurel, JPaez, DSastre, JAparicio, JBenavides, MFeliu, JVera, R2023-01-252023-01-252018-11-28Gómez-España MA, Gallego J, González-Flores E, Maurel J, Páez D, Sastre J, et al. SEOM clinical guidelines for diagnosis and treatment of metastatic colorectal cancer (2018). Clin Transl Oncol. 2019 Jan;21(1):46-54http://hdl.handle.net/10668/13328Colorectal cancer (CRC) is the second cause of cancer death in Spain, the objective of this guide published by the Spanish Society of Medical Oncology is to develop a consensus for the diagnosis and management of metastatic disease. The optimal treatment strategy for patients with metastatic CRC should be discussed in a multidisciplinary expert team to select the most appropriate treatment, and integrate systemic treatment and other options such as surgery and ablative techniques depending on the characteristics of the tumour, the patient and the location of the disease and metastases.enAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/Ablative treatmentsChemotherapyColorectal cancerFrail patientsMetastasesSurgeryTargeted agentsClinical trials as topicColorectal neoplasmsCombined modality therapyDisease managementHumansLiver neoplasmsPractice guidelines as topicPrognosisSocieties, medicalresearch article30565083open accessEnsayos clínicos como asuntoManejo de la enfermedadNeoplasias colorrectalesNeoplasias hepáticasSociedades médicasTerapia combinada10.1007/s12094-018-02002-w1699-3055PMC6339676https://link.springer.com/content/pdf/10.1007/s12094-018-02002-w.pdfhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339676/pdf