Jimeno, SoniaBalestra, Fernando R.Huertas, Pablo2022-10-072022-10-072021-04-29Jimeno S, Balestra FR, Huertas P. The Emerging Role of RNA Modifications in DNA Double-Strand Break Repair. Front Mol Biosci. 2021 Apr 29;8:664872http://hdl.handle.net/10668/4246The correct repair of DNA double-strand breaks is essential for maintaining the stability of the genome, thus ensuring the survival and fitness of any living organism. Indeed, the repair of these lesions is a complicated affair, in which several pathways compete for the DNA ends in a complex balance. Thus, the fine-tuning of the DNA double-strand break repair pathway choice relies on the different regulatory layers that respond to environmental cues. Among those different tiers of regulation, RNA modifications have just emerged as a promising field.enAtribución 4.0 Internacionalhttp://creativecommons.org/licenses/by/4.0/RNA modificationDNA repairHomologous recombinationDNA resectionR-loopProcesamiento postranscripcional del ARNReparación del ADNRecombinación homólogaEstructuras R-loopADNMedical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Damage::DNA Breaks::DNA Breaks, Double-StrandedMedical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::DNA::DNA, Single-StrandedMedical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Base SequenceMedical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Recombination, Genetic::Homologous RecombinationMedical Subject Headings::Phenomena and Processes::Genetic Phenomena::Sequence HomologyMedical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::NucleoproteinsMedical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biology::Genetics::GenomicsMedical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA RepairMedical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genomereview article33996910Acceso abierto10.3389/fmolb.2021.6648722296-889XPMC8116738