Peñalva, GermanDiaz-Högberg, LiselotteWeist, KlausVlahović-Palčevski, VeraHeuer, OleMonnet, Dominique L2023-02-082023-02-082019-11-14Peñalva G, Högberg LD, Weist K, Vlahović-Palčevski V, Heuer O, Monnet DL; et al. Decreasing and stabilising trends of antimicrobial consumption and resistance in Escherichia coli and Klebsiella pneumoniae in segmented regression analysis, European Union/European Economic Area, 2001 to 2018. Euro Surveill. 2019 Nov;24(46):1900656.http://hdl.handle.net/10668/14747Investments to reduce the spread of antimicrobial resistance (AMR) in the European Union have been made, including efforts to strengthen prudent antimicrobial use. Using segmented regression, we report decreasing and stabilising trends in data reported to the European Surveillance of Antimicrobial Consumption Network and stabilising trends in data reported to the European Antimicrobial Resistance Surveillance Network. Our results could be an early indication of the effect of prioritising AMR on the public health agenda.enAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/Antimicrobial consumptionEscherichia coliKlebsiella pneumoniaeantimicrobial resistancebacterial infectionscarbapenemdefined daily dosefluoroquinolonethird-generation cephalosporinAnti-Bacterial AgentsAntimicrobial StewardshipCephalosporinsDrug Resistance, Multiple, BacterialDrug UtilizationEscherichia coliEscherichia coli InfectionsEuropean UnionFluoroquinolonesHumansKlebsiella InfectionsKlebsiella pneumoniaeMicrobial Sensitivity TestsPopulation Surveillanceresearch article31771708open accessVigilancia en desastresInversiones en saludUnión EuropeaInforme de investigaciónSalud PúblicaEconomía10.2807/1560-7917.ES.2019.24.46.19006561560-7917PMC6864974https://www.eurosurveillance.org/deliver/fulltext/eurosurveillance/24/46/eurosurv-24-46-1.pdf?itemId=%2Fcontent%2F10.2807%2F1560-7917.ES.2019.24.46.1900656&mimeType=pdf&containerItemId=content/eurosurveillancehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864974/pdf