Sorlazano-Puerto, AntonioGomez-Luque, Jose MariaLuna-Del-Castillo, Juan de DiosNavarro-Mari, Jose MariaGutierrez-Fernandez, Jose2023-01-252023-01-252017-03-30Sorlózano-Puerto A, Gómez-Luque JM, Luna-Del-Castillo JD, Navarro-Marí JM, Gutiérrez-Fernández J. Etiological and Resistance Profile of Bacteria Involved in Urinary Tract Infections in Young Children. Biomed Res Int. 2017;2017:4909452.http://hdl.handle.net/10668/11191Background. The objective of this study was to identify the bacteria most frequently responsible for urinary tract infection (UTI) in the population of under-2-year-olds in our geographic area and to evaluate the activity of antibiotics widely used for UTI treatment during a 4-year study period. Materials and Methods. A retrospective analysis was conducted of data on the identification and susceptibility of microorganisms isolated in urine samples from children under 2 years of age. Results. A total of 1,045 uropathogens were isolated. Escherichia coli accounted for the majority (60.3%) of these, followed by Enterococcus faecalis (22.4%) and Klebsiella spp. (6.5%). The highest E. coli susceptibility rates (>90%) were to piperacillin-tazobactam, cefuroxime, cefotaxime, ceftazidime, imipenem, gentamicin, nitrofurantoin, and fosfomycin, and the lowest were to amoxicillin-clavulanic acid and cotrimoxazole. Among all bacteria isolated, we highlight the overall high activity of piperacillin-tazobactam, imipenem, nitrofurantoin, and fosfomycin against both community and hospital isolates and the reduced activity of amoxicillin-clavulanic acid, cephalosporins, gentamicin, and cotrimoxazole. There was no significant change in the total activity of any of the studied antibiotics over the 4-year study period. Conclusion. Empiric treatment with amoxicillin-clavulanic acid, cotrimoxazole, cephalosporins, and gentamicin may be inadequate due to their limited activity against uropathogens in our setting.enAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/Anti-Bacterial AgentsDrug Resistance, BacterialInfantBacteriaChild, PreschoolFemaleHumansMaleUrinary Tract Infectionsresearch article28497052open accessBacteriasFemeninoHumanosInfecciones urinariasMasculinoPreescolar10.1155/2017/49094522314-6141PMC5405357http://downloads.hindawi.com/journals/bmri/2017/4909452.pdfhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405357/pdf