Callejas, AntonioMelchor, JuanFaris, Inas H.Rus, Guillermo2022-04-262022-04-262020-08-05Callejas A, Melchor J, Faris IH, Rus G. Hyperelastic Ex Vivo Cervical Tissue Mechanical Characterization. Sensors. 2020 Aug 5;20(16):4362http://hdl.handle.net/10668/3571This paper presents the results of the comparison between a proposed Fourth Order Elastic Constants (FOECs) nonlinear model defined in the sense of Landau's theory, and the two most contrasted hyperelastic models in the literature, Mooney-Rivlin, and Ogden models. A mechanical testing protocol is developed to investigate the large-strain response of ex vivo cervical tissue samples in uniaxial tension in its two principal anatomical locations, the epithelial and connective layers. The final aim of this work is to compare the reconstructed shear modulus of the epithelial and connective layers of cervical tissue. According to the obtained results, the nonlinear parameter A from the proposed FOEC model could be an important biomarker in cervical tissue diagnosis. In addition, the calculated shear modulus depended on the anatomical location of the cervical tissue (μepithelial = 1.29 ± 0.15 MPa, and μconnective = 3.60 ± 0.63 MPa).enAtribución 4.0 Internacionalhttp://creativecommons.org/licenses/by/4.0/HyperelasticityUniaxial tensile testCervical tissueNonlinearityHyperelastic modelsDinámicas no linealesEnfermedades del cuello del úteroPruebas mecánicasBiomarcadoresElasticidadTejidosMedical Subject Headings::Phenomena and Processes::Physical Phenomena::Mechanical Phenomena::ElasticityMedical Subject Headings::Check Tags::FemaleMedical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::HumansMedical Subject Headings::Phenomena and Processes::Physical Phenomena::Mechanical Phenomena::Mechanical Processes::Stress, MechanicalMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models, Theoretical::Nonlinear DynamicsMedical Subject Headings::Diseases::Female Urogenital Diseases and Pregnancy Complications::Female Urogenital Diseases::Genital Diseases, Female::Uterine Diseases::Uterine Cervical DiseasesMedical Subject Headings::Chemicals and Drugs::Biological Factors::Biological MarkersHyperelastic Ex Vivo Cervical Tissue Mechanical Characterizationresearch article32764345Acceso abierto10.3390/s201643621424-8220PMC7472274