Arroyo-Olivares, RaquelAlonso, RodrigoQuintana-Navarro, GraciaFuentes-Jimenez, FranciscoMata, NelvaMuñiz-Grijalvo, OvidioDiaz-Diaz, Jose LZambon, DanielArrieta, FranciscoGarcia-Cruces, JesusGarrido-Sanjuan, Juan ABanegas, Jose RMata, Pedro2023-01-252023-01-252018-12-05Arroyo-Olivares R, Alonso R, Quintana-Navarro G, Fuentes-Jiménez F, Mata N, Muñiz-Grijalvo O, et al. Adults with familial hypercholesterolaemia have healthier dietary and lifestyle habits compared with their non-affected relatives: the SAFEHEART study. Public Health Nutr. 2019 Jun;22(8):1433-1443http://hdl.handle.net/10668/13531Healthy lifestyle habits are the cornerstone in the management of familial hypercholesterolaemia (FH). Nevertheless, dietary studies on FH-affected populations are scarce. The present study analyses dietary habits, adherence to a Mediterranean diet pattern and physical activity in an adult population with FH and compares them with their non-affected relatives. Cross-sectional study. Data came from SAFEHEART, a nationwide study in Spain.ParticipantsIndividuals (n 3714) aged ≥18 years with a genetic diagnosis of FH (n2736) and their non-affected relatives (n 978). Food consumption was evaluated using a validated FFQ. Total energy intake was lower in FH patients v. non-affected relatives (P<0·005). Percentage of energy from fats was also lower in the FH population (35 % in men, 36 % in women) v. those non-affected (38 % in both sexes, P<0·005), due to the lower consumption of saturated fats (12·1 % in FH patients, 13·2 % in non-affected, P<0·005). Consumption of sugars was lower in FH patients v. non-affected relatives (P<0·05). Consumption of vegetables, fish and skimmed milk was higher in the FH population (P<0·005). Patients with FH showed greater adherence to a Mediterranean diet pattern v. non-affected relatives (P<0·005). Active smoking was lower and moderate physical activity was higher in people with FH, especially women (P<0·005). Adult patients with FH report healthier lifestyles than their non-affected family members. They eat a healthier diet, perform more physical activity and smoke less. However, this patient group's consumption of saturated fats and sugars still exceeds guidelines.enDietFamilial hypercholesterolaemiaFatty acidsMediterranean dietPhysical activityAdultCross-sectional studiesDiet surveysDiet, mediterraneanExerciseFamilyFeeding behaviorFemaleHealthy lifestyleHumansHyperlipoproteinemia type IIMaleMiddle agedPatient complianceresearch article30732662open accessConducta alimentariaCooperación del pacienteDieta mediterráneaEjercicio físicoEncuestas sobre dietasEstilo de vida saludable10.1017/S13689800180038531475-2727https://www.cambridge.org/core/services/aop-cambridge-core/content/view/E7F90E7E04B8E56706C5B197C5EB5538/S1368980018003853a.pdf/div-class-title-adults-with-familial-hypercholesterolaemia-have-healthier-dietary-and-lifestyle-habits-compared-with-their-non-affected-relatives-the-safeheart-study-div.pdf